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Protein

Endolytic murein transglycosylase

Gene

mltG

Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei239Important for catalytic activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
Biological processCell wall biogenesis/degradationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Endolytic murein transglycosylaseUniRule annotation (EC:4.2.2.-UniRule annotation)
Alternative name(s):
Peptidoglycan polymerization terminaseUniRule annotation
Gene namesi
Name:mltGUniRule annotation
Ordered Locus Names:lmo1499Imported
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)Imported
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000817 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ8Y725.

Interactioni

Protein-protein interaction databases

STRINGi169963.lmo1499.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4IIWX-ray2.60A/B32-356[»]
ProteinModelPortaliQ8Y725.
SMRiQ8Y725.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transglycosylase MltG family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105HHA. Bacteria.
COG1559. LUCA.
HOGENOMiHOG000050564.
KOiK07082.
OMAiLVEGWTF.
PhylomeDBiQ8Y725.

Family and domain databases

CDDicd08010. yceG_like. 1 hit.
HAMAPiMF_02065. MltG. 1 hit.
InterProiView protein in InterPro
IPR003770. YceG.
PANTHERiPTHR30518:SF3. PTHR30518:SF3. 1 hit.
PfamiView protein in Pfam
PF02618. YceG. 1 hit.
TIGRFAMsiTIGR00247. TIGR00247. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8Y725-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKNTKGKKIT IIISIIILIL VIATFSGYYY VKSQLEPKDE ASKEKITVEI
60 70 80 90 100
PAGSSISDIS TILEDKKVIN NASIFSFYVK YNNDTNLKAG NYELSPAMNT
110 120 130 140 150
DQIVKKMQEG KTVAPAKLVI PEGYTLDQIA DRIVAYQPKL KKADVLKTMD
160 170 180 190 200
DPEFVASMIK AYPETVTNDV LNKSIKHPLE GYLYPATYTF KGTDVSAEQI
210 220 230 240 250
ITEMVKATDV NIAKYRDELT KQKMSVHKFL TMSSIIEKEA TENVDRKMIA
260 270 280 290 300
SVFYNRLAKD MRLQTDPTVL YALGEHKSKT TYKDLEVDSP YNTYKNNGLP
310 320 330 340 350
PGPISNSGDS SMEAALYPEK SDYLYFLANT KTGKVYFSKT LEEHNKLKEE

HITKNN
Length:356
Mass (Da):40,135
Last modified:March 1, 2002 - v1
Checksum:i754B3391048891E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591979 Genomic DNA. Translation: CAC99577.1.
PIRiAC1262.
RefSeqiNP_465024.1. NC_003210.1.
WP_003722008.1. NC_003210.1.

Genome annotation databases

EnsemblBacteriaiCAC99577; CAC99577; CAC99577.
GeneIDi987003.
KEGGilmo:lmo1499.
PATRICifig|169963.11.peg.1540.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ8Y725_LISMO
AccessioniPrimary (citable) accession number: Q8Y725
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 5, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported