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Protein

Uncharacterized RNA methyltransferase lmo1703

Gene

lmo1703

Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi76 – 761Iron-sulfur (4Fe-4S)By similarity
Metal bindingi82 – 821Iron-sulfur (4Fe-4S)By similarity
Metal bindingi85 – 851Iron-sulfur (4Fe-4S)By similarity
Metal bindingi166 – 1661Iron-sulfur (4Fe-4S)By similarity
Binding sitei290 – 2901S-adenosyl-L-methioninePROSITE-ProRule annotation
Binding sitei319 – 3191S-adenosyl-L-methionine; via carbonyl oxygenPROSITE-ProRule annotation
Binding sitei340 – 3401S-adenosyl-L-methioninePROSITE-ProRule annotation
Binding sitei388 – 3881S-adenosyl-L-methioninePROSITE-ProRule annotation
Active sitei415 – 4151NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. RNA binding Source: InterPro
  4. RNA methyltransferase activity Source: InterPro

GO - Biological processi

  1. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciLMON169963:LMO1703-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RNA methyltransferase lmo1703 (EC:2.1.1.-)
Gene namesi
Ordered Locus Names:lmo1703
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000000817 Componenti: Chromosome

Organism-specific databases

GenoListiLMO1703.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 459459Uncharacterized RNA methyltransferase lmo1703PRO_0000162001Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi169963.lmo1703.

Structurei

3D structure databases

ProteinModelPortaliQ8Y6I1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 6359TRAMPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.PROSITE-ProRule annotation
Contains 1 TRAM domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG2265.
HOGENOMiHOG000029867.
OMAiGFELEHM.
OrthoDBiEOG6V4GKM.
PhylomeDBiQ8Y6I1.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR001566. 23S_rRNA_MeTrfase_RlmD.
IPR030390. MeTrfase_TrmA_AS.
IPR030391. MeTrfase_TrmA_CS.
IPR012340. NA-bd_OB-fold.
IPR029063. SAM-dependent_MTases.
IPR002792. TRAM_dom.
IPR010280. U5_MeTrfase_fam.
[Graphical view]
PfamiPF01938. TRAM. 1 hit.
PF05958. tRNA_U5-meth_tr. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00479. rumA. 1 hit.
PROSITEiPS51687. SAM_MT_RNA_M5U. 1 hit.
PS50926. TRAM. 1 hit.
PS01230. TRMA_1. 1 hit.
PS01231. TRMA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Y6I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQNPVEEGQ KFPLTIRRMG INGEGIGYFK KAVVFVPGAI TGEEVVVEAV
60 70 80 90 100
KVRDRFTEAK LNKIRKKSPN RVTAPCPVYE ACGGCQLQHV AYSAQLELKR
110 120 130 140 150
DIVIQSIEKH TKIDPTKLKI RPTIGMEDPW RYRNKSQFQT RMVGSGQVET
160 170 180 190 200
GLFGANSHQL VPIEDCIVQQ PVTIKVTNFV RDLLEKYGVP IYDEKAGSGI
210 220 230 240 250
VRTIVVRTGV KTGETQLVFI TNSKKLPKKR EMLAEIEAAL PEVTSIMQNV
260 270 280 290 300
NQAKSSLIFG DETFLLAGKE SIEEKLMELE FDLSARAFFQ LNPFQTERLY
310 320 330 340 350
QEVEKALVLT GSETLVDAYC GVGTIGQAFA GKVKEVRGMD IIPESIEDAK
360 370 380 390 400
RNAEKNGIEN VYYEVGKAED VLPKWVKEGF RPDAVIVDPP RSGCDQGLIK
410 420 430 440 450
SLLDVEAKQL VYVSCNPSTL ARDLALLAKK YRIRYMQPVD MFPQTAHVET

VVLLQLKDK
Length:459
Mass (Da):51,325
Last modified:February 28, 2002 - v1
Checksum:iA582F57A42595F06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591981 Genomic DNA. Translation: CAC99781.1.
PIRiAG1287.
RefSeqiNP_465228.1. NC_003210.1.

Genome annotation databases

GeneIDi985603.
KEGGilmo:lmo1703.
PATRICi20312587. VBILisMon69206_1746.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591981 Genomic DNA. Translation: CAC99781.1.
PIRiAG1287.
RefSeqiNP_465228.1. NC_003210.1.

3D structure databases

ProteinModelPortaliQ8Y6I1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi169963.lmo1703.

Protocols and materials databases

DNASUi985603.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi985603.
KEGGilmo:lmo1703.
PATRICi20312587. VBILisMon69206_1746.

Organism-specific databases

GenoListiLMO1703.

Phylogenomic databases

eggNOGiCOG2265.
HOGENOMiHOG000029867.
OMAiGFELEHM.
OrthoDBiEOG6V4GKM.
PhylomeDBiQ8Y6I1.

Enzyme and pathway databases

BioCyciLMON169963:LMO1703-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR001566. 23S_rRNA_MeTrfase_RlmD.
IPR030390. MeTrfase_TrmA_AS.
IPR030391. MeTrfase_TrmA_CS.
IPR012340. NA-bd_OB-fold.
IPR029063. SAM-dependent_MTases.
IPR002792. TRAM_dom.
IPR010280. U5_MeTrfase_fam.
[Graphical view]
PfamiPF01938. TRAM. 1 hit.
PF05958. tRNA_U5-meth_tr. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00479. rumA. 1 hit.
PROSITEiPS51687. SAM_MT_RNA_M5U. 1 hit.
PS50926. TRAM. 1 hit.
PS01230. TRMA_1. 1 hit.
PS01231. TRMA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-679 / EGD-e.

Entry informationi

Entry nameiY1703_LISMO
AccessioniPrimary (citable) accession number: Q8Y6I1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 18, 2004
Last sequence update: February 28, 2002
Last modified: March 31, 2015
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.