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Protein

Adenine deaminase

Gene

ade

Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Enzyme and pathway databases

BioCyciLMON169963:G1GTA-1864-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Synonyms:adeC
Ordered Locus Names:lmo1742
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000817 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001424291 – 580Adenine deaminaseAdd BLAST580

Proteomic databases

PaxDbiQ8Y6E5

Interactioni

Protein-protein interaction databases

STRINGi169963.lmo1742

Structurei

3D structure databases

ProteinModelPortaliQ8Y6E5
SMRiQ8Y6E5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN Bacteria
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiHEIANVM
PhylomeDBiQ8Y6E5

Family and domain databases

CDDicd01295 AdeC, 1 hit
Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR01178 ade, 1 hit

Sequencei

Sequence statusi: Complete.

Q8Y6E5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVENLKQLQE RVAVSDGRAK ADLVIKNGRI INVFSGEIMD GDIAIKNGYI
60 70 80 90 100
AGIGSFPDAE KIIDAAGAFI APGFIDAHVH VESAMVTPAE FARVLLPNGV
110 120 130 140 150
TTIVTDPHEI ANVAGEKGIE FMLEDAKGAP LDMFVMLPSS VPATEGEHNG
160 170 180 190 200
ETLHAEKLHP LYRHEKVIGL AEVMDFPSVA KGSDDILRKI IDAKKEGGRI
210 220 230 240 250
DGHGAGLTSA DLNNYLAVGI RTDHESTTAK EATDRLRAGM FVMLREGTVG
260 270 280 290 300
RDLLQTIPAV SEKNSHRFCF CTDDKLINDL ITEGSINYNI KLAIKNGIDP
310 320 330 340 350
ITAIQMATIN AANCHNLPYL GAVAAGYQAD IVFLTDIETV EISKVLKNGE
360 370 380 390 400
VVVDNGVRNE AAFKQQAAVP FVSPPINHHV HLQDLALPLT KETCYVIGMQ
410 420 430 440 450
PNSLFTEKRI EQVTIQGGKF VPTVENDLLK MAVVERHHDT GCVGVGIVKG
460 470 480 490 500
FGLTEGAIAT TVAHDSHNIV AVGVSDEAMK AAIDHITQTG GGIAVVNGAG
510 520 530 540 550
QVLHDLALPI AGLLSDKSYE EVENDLAGLL NAFKQISTAN GFDPFLTLSF
560 570 580
LTLPVIPELK LTDQGLFDFA TFQIISNEVN
Length:580
Mass (Da):62,125
Last modified:March 1, 2002 - v1
Checksum:iC88B2DF4FA21EACB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591981 Genomic DNA Translation: CAC99820.1
PIRiAF1292
RefSeqiNP_465267.1, NC_003210.1
WP_010989802.1, NC_003210.1

Genome annotation databases

EnsemblBacteriaiCAC99820; CAC99820; CAC99820
GeneIDi985560
KEGGilmo:lmo1742
PATRICifig|169963.11.peg.1785

Similar proteinsi

Entry informationi

Entry nameiADEC_LISMO
AccessioniPrimary (citable) accession number: Q8Y6E5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health