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Protein

Adenine deaminase

Gene

ade

Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciLMON169963:LMO1742-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Synonyms:adeC
Ordered Locus Names:lmo1742
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000817 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 580580Adenine deaminasePRO_0000142429Add
BLAST

Proteomic databases

PaxDbiQ8Y6E5.

Interactioni

Protein-protein interaction databases

STRINGi169963.lmo1742.

Structurei

3D structure databases

ProteinModelPortaliQ8Y6E5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiYSHDSHN.
OrthoDBiEOG622PNM.
PhylomeDBiQ8Y6E5.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8Y6E5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVENLKQLQE RVAVSDGRAK ADLVIKNGRI INVFSGEIMD GDIAIKNGYI
60 70 80 90 100
AGIGSFPDAE KIIDAAGAFI APGFIDAHVH VESAMVTPAE FARVLLPNGV
110 120 130 140 150
TTIVTDPHEI ANVAGEKGIE FMLEDAKGAP LDMFVMLPSS VPATEGEHNG
160 170 180 190 200
ETLHAEKLHP LYRHEKVIGL AEVMDFPSVA KGSDDILRKI IDAKKEGGRI
210 220 230 240 250
DGHGAGLTSA DLNNYLAVGI RTDHESTTAK EATDRLRAGM FVMLREGTVG
260 270 280 290 300
RDLLQTIPAV SEKNSHRFCF CTDDKLINDL ITEGSINYNI KLAIKNGIDP
310 320 330 340 350
ITAIQMATIN AANCHNLPYL GAVAAGYQAD IVFLTDIETV EISKVLKNGE
360 370 380 390 400
VVVDNGVRNE AAFKQQAAVP FVSPPINHHV HLQDLALPLT KETCYVIGMQ
410 420 430 440 450
PNSLFTEKRI EQVTIQGGKF VPTVENDLLK MAVVERHHDT GCVGVGIVKG
460 470 480 490 500
FGLTEGAIAT TVAHDSHNIV AVGVSDEAMK AAIDHITQTG GGIAVVNGAG
510 520 530 540 550
QVLHDLALPI AGLLSDKSYE EVENDLAGLL NAFKQISTAN GFDPFLTLSF
560 570 580
LTLPVIPELK LTDQGLFDFA TFQIISNEVN
Length:580
Mass (Da):62,125
Last modified:March 1, 2002 - v1
Checksum:iC88B2DF4FA21EACB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591981 Genomic DNA. Translation: CAC99820.1.
PIRiAF1292.
RefSeqiNP_465267.1. NC_003210.1.
WP_010989802.1. NC_003210.1.

Genome annotation databases

EnsemblBacteriaiCAC99820; CAC99820; CAC99820.
GeneIDi985560.
KEGGilmo:lmo1742.
PATRICi20312667. VBILisMon69206_1785.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591981 Genomic DNA. Translation: CAC99820.1.
PIRiAF1292.
RefSeqiNP_465267.1. NC_003210.1.
WP_010989802.1. NC_003210.1.

3D structure databases

ProteinModelPortaliQ8Y6E5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi169963.lmo1742.

Proteomic databases

PaxDbiQ8Y6E5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC99820; CAC99820; CAC99820.
GeneIDi985560.
KEGGilmo:lmo1742.
PATRICi20312667. VBILisMon69206_1785.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiYSHDSHN.
OrthoDBiEOG622PNM.
PhylomeDBiQ8Y6E5.

Enzyme and pathway databases

BioCyciLMON169963:LMO1742-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-679 / EGD-e.

Entry informationi

Entry nameiADEC_LISMO
AccessioniPrimary (citable) accession number: Q8Y6E5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: March 1, 2002
Last modified: February 17, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.