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Q8Y691 (RNC_LISMO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Synonyms:rncS
Ordered Locus Names:lmo1805
OrganismListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [Reference proteome] [HAMAP]
Taxonomic identifier169963 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length229 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 229229Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000180409

Regions

Domain4 – 133130RNase III
Domain159 – 22870DRBM

Sites

Active site501 Potential
Active site1221 By similarity
Metal binding461Magnesium By similarity
Metal binding1191Magnesium By similarity
Metal binding1221Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Y691 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 6EC7E91DE1FA9107

FASTA22925,917
        10         20         30         40         50         60 
MNQWEELQES VGFDFKNVEL LKQAFTHSSY VNEHRRENVK DNERLEFLGD AVLELTVSDY 

        70         80         90        100        110        120 
LFNKYPDMAE GHMTKMRAAI VCEPSLVEFA EAVHFSKYVR LGKGEEKAGG RTRPALLADV 

       130        140        150        160        170        180 
FESFIGALYL DNGIDKVVTF LERVIFPKID AGAYLQTVDY KTQLQEIVQR DRDVLIEYDI 

       190        200        210        220 
LGETGPAHNK AFDAQVIVNG QVLGKGSGRT KKQAEQSAAQ FAINKLIHR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591981 Genomic DNA. Translation: CAC99883.1.
PIRAE1300.
RefSeqNP_465330.1. NC_003210.1.

3D structure databases

ProteinModelPortalQ8Y691.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING169963.lmo1805.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC99883; CAC99883; CAC99883.
GeneID985924.
KEGGlmo:lmo1805.
PATRIC20312801. VBILisMon69206_1849.

Organism-specific databases

GenoListLMO1805.

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
OMALTHKSCK.
OrthoDBEOG6T1WVS.
ProtClustDBPRK00102.

Enzyme and pathway databases

BioCycLMON169963:LMO1805-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_LISMO
AccessionPrimary (citable) accession number: Q8Y691
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: March 1, 2002
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families