Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q8Y5X6 (AROB_LISMO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:lmo1927
OrganismListeria monocytogenes
Taxonomic identifier1639 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3653653-dehydroquinate synthase HAMAP MF_00110
PRO_0000140754

Sequences

Sequence LengthMass (Da)Tools
Q8Y5X6 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 89B9E833A64BAA65

FASTA36541,127
        10         20         30         40         50         60 
MPEITVRAKS KTYPVYINEF ALEDIREKWT KSLAKFSHVF VLTDGHVAEL HKAKLDAVLA 

        70         80         90        100        110        120 
DLPVVTYYVA PNGEEAKTFR VYEDVMTKMI ETGLDRKAVL IAFGGGVIGD LGGFVAATYM 

       130        140        150        160        170        180 
RGIPFYQVPT TVLAHDSAVG GKVAINHPLG KNMIGNFYQP EAVIYDTQFF ATLPERELRS 

       190        200        210        220        230        240 
GFAEMIKHAL ISDLTLLRAL MDTFTEPKDF YTKDLTPFLQ RGIEIKANIV AQDETEQGVR 

       250        260        270        280        290        300 
AYLNFGHTFG HALEAYGNFG KWLHGEAITY GMIYALTMSE TIYGLDFDLA EFKTWLEQLG 

       310        320        330        340        350        360 
YDTTFDASVP FSKILENMRH DKKTTFNEIS MVLLEEIGKP VIFKADDDLI FETYKRVMRK 


GGNVI

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL591981 Genomic DNA. Translation: CAD00005.1.
PIRAG1315.
RefSeqNP_465451.1. NC_003210.1.

3D structure databases

ProteinModelPortalQ8Y5X6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID985753.
GenomeReviewsGene locus lmo1927 in contig AL591824_GR.
KEGGlmo:lmo1927.
PATRIC20313049. VBILisMon69206_1973.

Organism-specific databases

GenoListLMO1927.

Phylogenomic databases

HOGENOMHBG632303.
OMAAYLNFGH.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycLMON169963:LMO1927-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_LISMO
AccessionPrimary (citable) accession number: Q8Y5X6
Entry history
Integrated into UniProtKB/Swiss-Prot: August 13, 2002
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents