Reviewed, UniProtKB/Swiss-Prot Q8Y5U4 (FENR1_LISMO)

Names and origin

Protein names

Recommended name:
    Ferredoxin--NADP reductase 1
      Short name=Fd-NADP+ reductase 1
      Short name=FNR 1
    EC=1.18.1.2

Gene names

Ordered Locus Names:

lmo1961

Organism

Listeria monocytogenes [Complete proteome] [HAMAP]

Taxonomic identifier

1639 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	FAD binding Inferred from electronic annotation. Source: HAMAP NADP or NADPH binding Inferred from electronic annotation. Source: HAMAP ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 332	332	Ferredoxin--NADP reductase 1 HAMAP MF_01685		PRO_0000364871
Sites
	Binding site	35	1	FAD By similarity
	Binding site	43	1	FAD By similarity
	Binding site	48	1	FAD By similarity
	Binding site	88	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	123	1	FAD; via amide nitrogen By similarity
	Binding site	284	1	FAD By similarity
	Binding site	325	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8Y5U4-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: D5070F899851EB43	FASTA	332	36,394
	10 20 30 40 50 60 MPNEVYDVTI IGGGPIGLFS AFYSGLRSMK TKIIDAEPAV GGKVRYFFPE KIIRDIGGIP 70 80 90 100 110 120 AITGENLVAN LKQQAETFHP TIVCSERVVD VTKLADGTFQ LTSHNGSIHF SKTIVIATGS 130 140 150 160 170 180 GTFEVNKLEA LHAEDFPFAI HYDVKNIEQF RDKVVVVSGG GNSAIDWAQT LEPIAKKVHL 190 200 210 220 230 240 IYRGEDFKAH EESVRELKNS RVEIHIHHEI SELIGTNNQL TEITVCCNQT QTTKTIETEA 250 260 270 280 290 300 LFINHGVKVD LGTMAEWGFK QADFGIVVDD EMKTTVPGIF ACGDSATYPR KIRIIAAGLH 310 320 330 EGPIAINSAK KYLEPTAADE AMISTHHESF IG

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed: 11679669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-679 / EGD-e / Serovar 1/2a.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL591981 Genomic DNA. Translation: CAD00039.1.
PIR	AI1319.
RefSeq	NP_465485.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	984397.
GenomeReviews	Gene locus lmo1961 in contig AL591824_GR.
KEGG	lmo:lmo1961.
Organism-specific databases
ListiList	LMO1961.
CMR	Search...
Phylogenomic databases
HOGENOM	Q8Y5U4.
OMA	KKVYVTY.
Enzyme and pathway databases
BioCyc	LMON169963:LMO1961-MON.
Family and domain databases
HAMAP	MF_01685. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR001327. Pyr_OxRdtase_NAD_bd. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

FENR1_LISMO

Accession

Primary (citable) accession number: Q8Y5U4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)