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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei290 – 2901Proton donorUniRule annotation
Active sitei311 – 3111UniRule annotation
Active sitei425 – 4251UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLMON169963:LMO2367-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:lmo2367
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000000817 Componenti: Chromosome

Organism-specific databases

GenoListiLMO2367.

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Glucose-6-phosphate isomerasePRO_0000180668Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi169963.lmo2367.

Structurei

3D structure databases

ProteinModelPortaliQ8Y4R7.
SMRiQ8Y4R7. Positions 4-448.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.
PhylomeDBiQ8Y4R7.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Y4R7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHIKFDYSK ALRFFEEREL DYLEPAVKAA HDSLHNGTGA GNDALGWINL
60 70 80 90 100
PTDYDKEEFA RIKKATEKIH SDSDVLIVIG IGGSYLGARA AIETLNHSFY
110 120 130 140 150
NVLEKGARKT PQVFFAGNSI SSSYLHDLIE VVGDRDFSVN VISKSGTTTE
160 170 180 190 200
PAIAFRVFKE LLIKKYGEEG AKKRIYATTD KAKGALKTLS DNEGYETFVV
210 220 230 240 250
PDDVGGRFSV LTAVGLLPIA VSGVDIDALM NGAAAASKDF DKPELKNNIA
260 270 280 290 300
YQYAAARNVL YRKGKVTELL ISYEPGLQYF NEWWKQLFGE SEGKDKKGIY
310 320 330 340 350
PSSANFSTDL HSIGQYIQDG RRNLFETVIK VDKPRHNLTI NKEDVDLDGL
360 370 380 390 400
NYLAGETVDF VNTKAFEGTL LAHTDGEVPN FVVEVPELDA YTFGYLVYFF
410 420 430 440 450
EKAVAISGYL NGVNPFDQPG VEAYKANMFA LLGKPGFEDK KAELEKRLND
Length:450
Mass (Da):49,896
Last modified:March 26, 2002 - v1
Checksum:iBBEA4511F99D8894
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591983 Genomic DNA. Translation: CAD00445.1.
PIRiAG1370.
RefSeqiNP_465890.1. NC_003210.1.

Genome annotation databases

GeneIDi984404.
KEGGilmo:lmo2367.
PATRICi20314004. VBILisMon69206_2425.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591983 Genomic DNA. Translation: CAD00445.1.
PIRiAG1370.
RefSeqiNP_465890.1. NC_003210.1.

3D structure databases

ProteinModelPortaliQ8Y4R7.
SMRiQ8Y4R7. Positions 4-448.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi169963.lmo2367.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi984404.
KEGGilmo:lmo2367.
PATRICi20314004. VBILisMon69206_2425.

Organism-specific databases

GenoListiLMO2367.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.
PhylomeDBiQ8Y4R7.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciLMON169963:LMO2367-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-679 / EGD-e.

Entry informationi

Entry nameiG6PI_LISMO
AccessioniPrimary (citable) accession number: Q8Y4R7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 26, 2002
Last sequence update: March 26, 2002
Last modified: March 31, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.