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Q8Y4R7 (G6PI_LISMO) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:lmo2367
OrganismListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [Reference proteome] [HAMAP]
Taxonomic identifier169963 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 450450Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180668

Sites

Active site2901Proton donor By similarity
Active site3111 By similarity
Active site4251 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Y4R7 [UniParc].

Last modified March 27, 2002. Version 1.
Checksum: BBEA4511F99D8894

FASTA45049,896
        10         20         30         40         50         60 
MTHIKFDYSK ALRFFEEREL DYLEPAVKAA HDSLHNGTGA GNDALGWINL PTDYDKEEFA 

        70         80         90        100        110        120 
RIKKATEKIH SDSDVLIVIG IGGSYLGARA AIETLNHSFY NVLEKGARKT PQVFFAGNSI 

       130        140        150        160        170        180 
SSSYLHDLIE VVGDRDFSVN VISKSGTTTE PAIAFRVFKE LLIKKYGEEG AKKRIYATTD 

       190        200        210        220        230        240 
KAKGALKTLS DNEGYETFVV PDDVGGRFSV LTAVGLLPIA VSGVDIDALM NGAAAASKDF 

       250        260        270        280        290        300 
DKPELKNNIA YQYAAARNVL YRKGKVTELL ISYEPGLQYF NEWWKQLFGE SEGKDKKGIY 

       310        320        330        340        350        360 
PSSANFSTDL HSIGQYIQDG RRNLFETVIK VDKPRHNLTI NKEDVDLDGL NYLAGETVDF 

       370        380        390        400        410        420 
VNTKAFEGTL LAHTDGEVPN FVVEVPELDA YTFGYLVYFF EKAVAISGYL NGVNPFDQPG 

       430        440        450 
VEAYKANMFA LLGKPGFEDK KAELEKRLND 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591983 Genomic DNA. Translation: CAD00445.1.
PIRAG1370.
RefSeqNP_465890.1. NC_003210.1.

3D structure databases

ProteinModelPortalQ8Y4R7.
SMRQ8Y4R7. Positions 4-448.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING169963.lmo2367.

PTM databases

PhosSiteP12011228.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD00445; CAD00445; CAD00445.
GeneID984404.
KEGGlmo:lmo2367.
PATRIC20314004. VBILisMon69206_2425.

Organism-specific databases

GenoListLMO2367.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAGVESYKR.
OrthoDBEOG64R61J.
PhylomeDBQ8Y4R7.

Enzyme and pathway databases

BioCycLMON169963:LMO2367-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_LISMO
AccessionPrimary (citable) accession number: Q8Y4R7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: March 27, 2002
Last modified: July 9, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways