Q8Y4P5 (FENR2_LISMO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase 2
Short name=FNR 2
Short name=Fd-NADP+ reductase 2
EC=1.18.1.2

Gene names

Ordered Locus Names:

lmo2390

Organism

Listeria monocytogenes

Taxonomic identifier

1639 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Ferredoxin--NADP reductase 2 HAMAP MF_01685		PRO_0000364872
Sites
	Binding site	37	1	FAD By similarity
	Binding site	45	1	FAD By similarity
	Binding site	50	1	FAD By similarity
	Binding site	90	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	124	1	FAD; via amide nitrogen By similarity
	Binding site	286	1	FAD By similarity
	Binding site	327	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8Y4P5 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 719AE5F923BC58B0	FASTA	331	36,426
	10 20 30 40 50 60 MDEKTKIYDI TIIGGGPVGL FAAFYAGMRN ASVKIIESLP QLGGQLSTLY PEKYIYDIPG 70 80 90 100 110 120 YPSVRAQELV NNLIQQMKPF DPTVALEEAV QSVEKQVDGT FEIITKKDTH YSKAIIITAG 130 140 150 160 170 180 NGAFEPRRLD LPEAEQYEGT NIHYFINDLS RFSGRRVAVC GGGDSAVDWA LMLEKVASSV 190 200 210 220 230 240 AIVHRRNAFR AHEHSVNNLE KSSIAIKTPF IPTEVLGNGD KLTHITLQEV KGDTTETLEI 250 260 270 280 290 300 DDFIINYGFV SSLGPIKNWG LELERNSIVV NSKMETSIPG IYCAGDICTY DGKVKLIATG 310 320 330 FGEAPTAVNN AMNFIDPKTR VQPMHSTSLF E

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed: 11679669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-679 / EGD-e / Serovar 1/2a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591983 Genomic DNA. Translation: CAD00468.1.
PIR	AF1373.
RefSeq	NP_465913.1. NC_003210.1.
3D structure databases
HSSP	HSSP built from PDB template 1TRB based on UniProtKB P0A9P4.
ProteinModelPortal	Q8Y4P5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	987545.
GenomeReviews	Gene locus lmo2390 in contig AL591824_GR.
KEGG	lmo:lmo2390.
PATRIC	20314050. VBILisMon69206_2448.
Organism-specific databases
GenoList	LMO2390.
Phylogenomic databases
HOGENOM	HBG669726.
OMA	FQVFELG.
ProtClustDB	CLSK2461576.
Enzyme and pathway databases
BioCyc	LMON169963:LMO2390-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR2_LISMO

Accession

Primary (citable) accession number: Q8Y4P5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program