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Q8Y4I2

- PGK_LISMO

UniProt

Q8Y4I2 - PGK_LISMO

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Protein

Phosphoglycerate kinase

Gene
pgk, lmo2458
Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei119 – 1191Substrate By similarity
Binding sitei156 – 1561Substrate By similarity
Binding sitei206 – 2061ATP By similarity
Binding sitei294 – 2941ATP; via carbonyl oxygen By similarity
Binding sitei325 – 3251ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi352 – 3554ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLMON169963:LMO2458-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:lmo2458
OrganismiListeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Taxonomic identifieri169963 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000000817: Chromosome

Organism-specific databases

GenoListiLMO2458.

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 396396Phosphoglycerate kinaseUniRule annotationPRO_0000145962Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi169963.lmo2458.

Structurei

3D structure databases

ProteinModelPortaliQ8Y4I2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.
PhylomeDBiQ8Y4I2.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Y4I2-1 [UniParc]FASTAAdd to Basket

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MAKKVVTDLD LKDKKVLVRV DFNVPMKDGK ITNDNRIVAA LPTIEYILEQ    50
NGKAILFSHL GKVKTEEDKE GKSLRPVAVR LSELLGKEVK FVPTTRGPEL 100
EKAIDELKDG EVLLFENTRF EDIDGKKESK NDPELGKYWA SLGDVFVNDA 150
FGTAHRAHAS NVGIASNLES AAGFLMEKEI KFIGGVVDNP ARPLVAILGG 200
AKVSDKIGVI ENLLTKADKV LVGGGMTFTF MAAQGQEIGK SLLEADKVEL 250
AKGLLEKAGD KLVLPVDAVV SKEFSNDAPF HTVSADSIPA DEMGLDIGQA 300
TIDLFTKELQ GAKTVVWNGP MGVFELSNFA KGTIGVCEAI ANLTDATTII 350
GGGDSAAAAM DLGFADKFTH ISTGGGASLE YLEGKELPGV ASISDK 396
Length:396
Mass (Da):42,104
Last modified:March 1, 2002 - v1
Checksum:i0D9D135473FA6E04
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL591983 Genomic DNA. Translation: CAD00536.1.
PIRiAB1382.
RefSeqiNP_465981.1. NC_003210.1.

Genome annotation databases

EnsemblBacteriaiCAD00536; CAD00536; CAD00536.
GeneIDi987378.
KEGGilmo:lmo2458.
PATRICi20314189. VBILisMon69206_2517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL591983 Genomic DNA. Translation: CAD00536.1 .
PIRi AB1382.
RefSeqi NP_465981.1. NC_003210.1.

3D structure databases

ProteinModelPortali Q8Y4I2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 169963.lmo2458.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD00536 ; CAD00536 ; CAD00536 .
GeneIDi 987378.
KEGGi lmo:lmo2458.
PATRICi 20314189. VBILisMon69206_2517.

Organism-specific databases

GenoListi LMO2458.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi WEALDIG.
OrthoDBi EOG64N9Z0.
PhylomeDBi Q8Y4I2.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci LMON169963:LMO2458-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-679 / EGD-e.

Entry informationi

Entry nameiPGK_LISMO
AccessioniPrimary (citable) accession number: Q8Y4I2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: March 1, 2002
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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