ID   Q8Y3W1_LISMO            Unreviewed;       525 AA.
AC   Q8Y3W1;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=Lmo2720 protein {ECO:0000313|EMBL:CAD00933.1};
GN   OrderedLocusNames=lmo2720 {ECO:0000313|EMBL:CAD00933.1};
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963 {ECO:0000313|EMBL:CAD00933.1, ECO:0000313|Proteomes:UP000000817};
RN   [1] {ECO:0000313|EMBL:CAD00933.1, ECO:0000313|Proteomes:UP000000817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e {ECO:0000313|Proteomes:UP000000817};
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.D.,
RA   Fsihi H., Portillo F.G., Garrido P., Gautier L., Goebel W., Gomez-Lopez N.,
RA   Hain T., Hauf J., Jackson D., Jones L.M., Kaerst U., Kreft J., Kuhn M.,
RA   Kunst F., Kurapkat G., Madueno E., Maitournam A., Vicente J.M., Ng E.,
RA   Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.C.,
RA   Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A.,
RA   Vazquez-Boland J.A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000256|ARBA:ARBA00006432}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL591984; CAD00933.1; -; Genomic_DNA.
DR   PIR; AG1414; AG1414.
DR   RefSeq; NP_466242.1; NC_003210.1.
DR   RefSeq; WP_010990048.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y3W1; -.
DR   STRING; 169963.gene:17595437; -.
DR   PaxDb; 169963-lmo2720; -.
DR   EnsemblBacteria; CAD00933; CAD00933; CAD00933.
DR   GeneID; 987095; -.
DR   KEGG; lmo:lmo2720; -.
DR   PATRIC; fig|169963.11.peg.2786; -.
DR   eggNOG; COG0365; Bacteria.
DR   HOGENOM; CLU_000022_59_10_9; -.
DR   OrthoDB; 9778383at2; -.
DR   PhylomeDB; Q8Y3W1; -.
DR   BioCyc; LMON169963:LMO2720-MONOMER; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0016405; F:CoA-ligase activity; IEA:UniProt.
DR   GO; GO:0015645; F:fatty acid ligase activity; IBA:GO_Central.
DR   GO; GO:0004321; F:fatty-acyl-CoA synthase activity; IBA:GO_Central.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IBA:GO_Central.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IBA:GO_Central.
DR   CDD; cd05972; MACS_like; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43605:SF10; ACYL-COA SYNTHETASE MEDIUM CHAIN FAMILY MEMBER 3; 1.
DR   PANTHER; PTHR43605; ACYL-COENZYME A SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000817}.
FT   DOMAIN          19..381
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          431..509
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   525 AA;  59157 MW;  9AAF575D9168B05A CRC64;
     MNSENLIAPE LYNITDEIAK FSSEKTALIW KNEHGETKTW SYHHLLEQAN KFANVAKDAG
     IKKGDHVIVM TPRLLETYAI YMGLWKAGAI IIPASELLKA HDLEYRIHHA NVKAIVSYNG
     MTAEFDKIES IPSVSKKIIV GDKLSGWEQY ETLMEAAPTE FERVETSRDD ACLLAFTSGT
     TGNPKGVVHI HGWGYAHIRI AADHWLDIHE DDIVWATAGP GWQKWVWSPF LSVLGKGATG
     FIYNGRFIPE KQLHLLEEEK INVLCCTPTE YRLMAKVNNL REHDLSSLRS AVSAGEPLNR
     EVIQVFRDNF DIKVRDGYGQ TESTLLIGTL VDTPIRPGSM GKPIMPEYMA IIDADGNPVG
     VGEIGDIAMR RDFPALFKEY YKEPERLQKA IRGDYFVSGD RAIRDEDNYY WFQGRNDDII
     ISSGYTIGPF EVEDALTHHP AVKEVAVVAS PDEIRGTVVK AFIVVKDGYK GTDDLVHELQ
     TFTKEQTAPY KYPRRIEFVE ALPKTDSGKI RRVELRDAEF ASVHG
//