Reviewed, UniProtKB/Swiss-Prot Q8Y3P9 (CATA_LISMO)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:	kat
Ordered Locus Names:	lmo2785

Organism

Listeria monocytogenes [Complete proteome] [HAMAP]

Taxonomic identifier

1639 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Cytoplasm
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 488	488	Catalase		PRO_0000085016
Sites
	Active site	55	1	By similarity
	Active site	128	1	By similarity
	Metal binding	338	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8Y3P9-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 95EB6097F5591734	FASTA	488	55,888
	10 20 30 40 50 60 MTDRKNLTTN QGVPVGDNQN SMTAGRKGPT LIEDYVLIEK LAHFDRERVP ERVVHARGAG 70 80 90 100 110 120 AHGKFVTKKS MKKYTMAKFL QEEGTETEVF ARFSTVIHGQ HSPETLRDPR GFSVKFYTEE 130 140 150 160 170 180 GNYDFVGNNL PVFFIRDAIK FPDVIHSLKP DPRTNIQDGN RYWDFFSLTP EATTMIMYLF 190 200 210 220 230 240 SDEGTPASYR EVRGSSVHAF KWINEEGKTV YVKLRWVPKA GIVNLSTEQA SQIQAKEFNH 250 260 270 280 290 300 ASRDLYEAIE NGDYPEWDLY VQVLDPKDLD SFDFNPLDAT KDWFEDVFPY EHVGTMTLDR 310 320 330 340 350 360 NPDNIFAETE SVGFNPGVLV RGMLPSEDRL LQGRLFSYSD TQRHRVGPNY LQLPINSPKA 370 380 390 400 410 420 PVANNQRDGH MPFKQQTSSI NYEPNSYDTE PKENPAFIEP EQEIRGDISG RLIAEKPNNF 430 440 450 460 470 480 GHAKEVWDRY SNAERAALVK NIVDDWSQVR EDIKIRNLRN FYQVDPEFAS RVAAGTGINL EEHVTDLK

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed: 11679669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-679 / EGD-e / Serovar 1/2a.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL591984 Genomic DNA. Translation: CAD00998.1.
PIR	AH1422.
RefSeq	NP_466307.1.
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Genome annotation databases
GeneID	984948.
GenomeReviews	Gene locus lmo2785 in contig AL591824_GR.
KEGG	lmo:lmo2785.
Organism-specific databases
ListiList	LMO02785.
CMR	Search...
Phylogenomic databases
HOGENOM	Q8Y3P9.
OMA	Q8Y3P9. SSINYEP.
Enzyme and pathway databases
BioCyc	LMON169963:LMO2785-MON.
BRENDA	1.11.1.6. 96770.
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_LISMO

Accession

Primary (citable) accession number: Q8Y3P9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2002
Last sequence update:	March 1, 2002
Last modified:	June 16, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)