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Q8Y2X7

- TYPH_RALSO

UniProt

Q8Y2X7 - TYPH_RALSO

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Protein

Putative thymidine phosphorylase

Gene

RSc0204

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciRSOL267608:GCVU-205-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:RSc0204
ORF Names:RS00636
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000001436: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 507507Putative thymidine phosphorylasePRO_0000059096Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267608.RSc0204.

Structurei

3D structure databases

ProteinModelPortaliQ8Y2X7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiFINGVRD.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8Y2X7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLAPPEVAAL PDRLTFKPLG IDTWQEHVIY MHPDCAICRA EGFTAQARVE
60 70 80 90 100
VRIGLRSLIA TLNLVGSGLL EMCEVSLSVS AVETLMARPG DIVTVSHAPA
110 120 130 140 150
LESLRAVRAK IYGAHLDTHQ LASVVGDIAK ERYADVHIAA FLSACAGGRM
160 170 180 190 200
SVKETIDLTQ AMVDSGECLE WDREIVADKH CVGGLPGNRT SPIVVAIAAA
210 220 230 240 250
AGLLLPKTSS RAITSPAGTA DTMETLTRVA LSATELRRVV DRVGASLAWG
260 270 280 290 300
GALSLSPADD VLIRVERALD VDSDAQLAAS ILSKKIAAGS THVLIDVPVG
310 320 330 340 350
PTAKVRSLQD LERLRMLLER VARSFGVRVT IVRTDGSQPV GRGIGPALEA
360 370 380 390 400
RDVLAVLQRS PAAPFDLRER SLLLAATLLE FCGAVEQGAG LEMATGVLDS
410 420 430 440 450
GAAWRKFEEI CEAQGGLRVP GEAIFRRDVV AEQDGIVTEI DNRHLARIAK
460 470 480 490 500
LAGAPMRQVA GVEMHVRLHD QVKAGRPLFT IHAQASGELE YSVAYALMHP

AVSIAPT
Length:507
Mass (Da):53,886
Last modified:March 1, 2002 - v1
Checksum:iDF121AC8CB2489AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA. Translation: CAD13732.1.
RefSeqiNP_518325.1. NC_003295.1.

Genome annotation databases

EnsemblBacteriaiCAD13732; CAD13732; RSc0204.
GeneIDi1219007.
KEGGirso:RSc0204.
PATRICi20258949. VBIRalSol70888_0209.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA. Translation: CAD13732.1 .
RefSeqi NP_518325.1. NC_003295.1.

3D structure databases

ProteinModelPortali Q8Y2X7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 267608.RSc0204.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD13732 ; CAD13732 ; RSc0204 .
GeneIDi 1219007.
KEGGi rso:RSc0204.
PATRICi 20258949. VBIRalSol70888_0209.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi FINGVRD.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci RSOL267608:GCVU-205-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GMI1000.

Entry informationi

Entry nameiTYPH_RALSO
AccessioniPrimary (citable) accession number: Q8Y2X7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3