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Q8Y2P8 (SYR_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:RSc0287
ORF Names:RS03254
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length600 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 600600Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151595

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q8Y2P8 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: E02008F9FA98355C

FASTA60065,085
        10         20         30         40         50         60 
MLPSHKQTIS QLLSDAVGTL LPEGTNRPEI VLERPKQAAH GDIACNVALQ LAKPLGTNPR 

        70         80         90        100        110        120 
ELANRIADGI RADARGQRLV SAVEIAGPGF INLRLSPTAR TDVLAAVFAE GDRYGAADLH 

       130        140        150        160        170        180 
DGAPVLVEFV SANPTGPLHV GHGRQAALGD ALAALLEWQG HKVHREFYYN DAGVQIHNLA 

       190        200        210        220        230        240 
VSVQARARGF KPGDTGWPEA AYNGDYIADI AADYLAGKTV RASDGEPVTG ARDVENIEAI 

       250        260        270        280        290        300 
RRFAVTYLRN EQDIDLQAFG VKFDHYYLES SLYADGKVQQ TVDALIAAGK TYEQEGALWL 

       310        320        330        340        350        360 
RTTDDGDDKD RVMRKSDGSY TYFVPDVAYH TTKWGRGFTQ VINVQGSDHH GTIARVRAGL 

       370        380        390        400        410        420 
QGLDLGIPKG YPDYVLHKMV TVMKDGAEVK ISKRAGSYVT VRDLIEWSNG DAESEAGVDT 

       430        440        450        460        470        480 
IRACVESGAP NWPGRFTRGR DAVRFFLLSR KADTEFVFDV DLALKQSDEN PVYYVQYAHA 

       490        500        510        520        530        540 
RICSVFEQWH AREGGDAASL AGADLAAVAG PEASPQAVAL VQRIAAFPDM LADAARELAP 

       550        560        570        580        590        600 
HAVAFYLRDL AGDFHAFYNA DRVLVDDDAV KRARLALLAA TRQVLRNGLA VIGVSAPQKM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646052 Genomic DNA. Translation: CAD13815.1.
RefSeqNP_518408.1. NC_003295.1.

3D structure databases

ProteinModelPortalQ8Y2P8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSc0287.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD13815; CAD13815; RSc0287.
GeneID1219090.
KEGGrso:RSc0287.
PATRIC20259115. VBIRalSol70888_0292.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-288-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RALSO
AccessionPrimary (citable) accession number: Q8Y2P8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: March 1, 2002
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries