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Q8Y1W6 (PGK_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:RSc0571
ORF Names:RS04894
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 419419Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145991

Regions

Nucleotide binding367 – 3704ATP By similarity
Region42 – 443Substrate binding By similarity
Region81 – 844Substrate binding By similarity

Sites

Binding site581Substrate By similarity
Binding site1351Substrate By similarity
Binding site1681Substrate By similarity
Binding site2191ATP By similarity
Binding site3411ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Y1W6 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 82192410852E3D81

FASTA41943,269
        10         20         30         40         50         60 
MASGKIAAFR DFSAAAMPNV LRLTDLISEG KLAGKRVFIR ADLNVPQDDA GNITEDTRIR 

        70         80         90        100        110        120 
ASVPAIRAAL DAGAAVMVTS HLGRPTEGEF KPEDSLAPVA VRLSELLGCE VKLVQNWVDG 

       130        140        150        160        170        180 
VDVAPGQVVL LENCRVNKGE KKNSDELAQK MAKLCDVYVN DAFGTAHRAE ATTHGIAKFA 

       190        200        210        220        230        240 
PIACAGPLLG AELDALGKAL GQPARPLVAI VAGSKVSTKL TILKSLADKV DNLIVGGGIA 

       250        260        270        280        290        300 
NTFMLAAGLK IGKSLAEADL VGDAKAIIDL MAARGASVPI PVDVVCAKEF SATAAATVKD 

       310        320        330        340        350        360 
VKDVADDDMI LDIGPKTAAQ LADQLKASGT IVWNGPVGVF EFDQFGNGTK VLAEAIAASS 

       370        380        390        400        410 
GFSIAGGGDT LAAIAKYGIA DRVGYISTGG GAFLEFLEGK TLPAVEILEQ RAQRQEALA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646052 Genomic DNA. Translation: CAD14101.1.
RefSeqNP_518692.1. NC_003295.1.

3D structure databases

ProteinModelPortalQ8Y1W6.
SMRQ8Y1W6. Positions 19-414.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSc0571.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD14101; CAD14101; RSc0571.
GeneID1219376.
KEGGrso:RSc0571.
PATRIC20259737. VBIRalSol70888_0601.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAAGHPVGK.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-574-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_RALSO
AccessionPrimary (citable) accession number: Q8Y1W6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways