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Q8Y1I9 (UPPP_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:RSc0701
ORF Names:RS01606
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 293293Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151184

Regions

Transmembrane3 – 2321Helical; Potential
Transmembrane43 – 6321Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane109 – 12921Helical; Potential
Transmembrane203 – 22321Helical; Potential
Transmembrane238 – 25821Helical; Potential
Transmembrane269 – 28921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8Y1I9 [UniParc].

Last modified March 5, 2002. Version 1.
Checksum: EA353CBD53ACD6B0

FASTA29332,256
        10         20         30         40         50         60 
MDIALAIKAL ILGIVEGLTE FLPISSTGHL ILAGQLLDFN DEKGKIFEIV IQFGAILAVC 

        70         80         90        100        110        120 
WEFRHKIIDV IKGLPNDPRQ QRFALNVIVA TIPAITLALI FGKAIKAHLF NPIVVASAFI 

       130        140        150        160        170        180 
IGGLVILWAE WRERHRGQTH DPRGNALLEA AKAGAPRVET LDDLRLSDAF KVGLAQCFAL 

       190        200        210        220        230        240 
IPGTSRSGST IIGGLLFGLS RKVATEFSFF LAIPVIFGAT VYELYKERAL LSTDDLSIFG 

       250        260        270        280        290 
IGFVAAFISA FFCVRWLLRF IASHDFRGFA WYRIVFGVIV LVTAYTHLIA WQA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646052 Genomic DNA. Translation: CAD14231.1.
RefSeqNP_518822.1. NC_003295.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSc0701.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD14231; CAD14231; RSc0701.
GeneID1219506.
KEGGrso:RSc0701.
PATRIC20260007. VBIRalSol70888_0736.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAFNDAHAK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-704-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_RALSO
AccessionPrimary (citable) accession number: Q8Y1I9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: May 14, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families