Q8Y1D0 (KYNB_RALSO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Kynurenine formamidase
Short name=KFA
EC=3.5.1.9

Alternative name(s):
N-formylkynurenine formamidase

Gene names

Name:	kynB
Ordered Locus Names:	RSc0760

Organism

Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine By similarity.
Catalytic activity	N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
Pathway	Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.
Sequence similarities	Belongs to the kynB family.

Ontologies

Keywords
Biological process	Tryptophan catabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arylformamidase activity Inferred from sequence or structural similarity. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	Kynurenine formamidase		PRO_0000362137

Sequences

	Sequence		Length	Mass (Da)
	Q8Y1D0-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: F760461F6E7078B9	FASTA	209	22,347
	10 20 30 40 50 60 MERTLWDISP ALSTATPTWP GDTPFSQEIA WKLEGDCPVN VGRITLSPHT GAHADAPLHY 70 80 90 100 110 120 HADGAPIGAV PLDAYLGPCR VIHCVGVARV EPEHVRDALD GAPPRVLLRT YARMPQNAWD 130 140 150 160 170 180 DHFAAVAPET IGLLAAHGVR LIGTDTASLD PQTSKTMDAH HAVGRHGLAI LEGLVLDDVP 190 200 AGDYELIALP LKFATLDASP VRAVLRRLP

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL646052 Genomic DNA. Translation: CAD14290.1.
RefSeq	NP_518881.1.
3D structure databases
ProteinModelPortal	Q8Y1D0.
SMR	Q8Y1D0. Positions 4-206.
ModBase	Search...
Genome annotation databases
GeneID	1219567.
GenomeReviews	Gene locus RSc0760 in contig AL646052_GR.
KEGG	rso:RSc0760.
NMPDR	fig|267608.1.peg.760.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG686791.
OMA	CPVNVGR.
ProtClustDB	CLSK2302456.
Enzyme and pathway databases
BioCyc	RSOL267608:RSC0760-MONOMER.
Family and domain databases
InterPro	IPR017484. Arylformamidase. IPR007325. Cyclase. [Graphical view]
Pfam	PF04199. Cyclase. 1 hit. [Graphical view]
TIGRFAMs	TIGR03035. trp_arylform. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KYNB_RALSO

Accession

Primary (citable) accession number: Q8Y1D0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	March 1, 2002
Last modified:	August 10, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)