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Q8Y199 (SYQ_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:RSc0791
ORF Names:RS05046
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length580 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 580580Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000195846

Regions

Motif51 – 6111"HIGH" region HAMAP-Rule MF_00126
Motif294 – 2985"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2971ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Y199 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: AA6C3A8783EA769C

FASTA58065,607
        10         20         30         40         50         60 
MSQDNATGAA AASTSNFLRQ IIDTDLEQGT YAGRQDTAGH ALPPIITRFP PEPNGYLHIG 

        70         80         90        100        110        120 
HAKSIWVNFG LAKEYGGRCH LRFDDTNPVK EDTEYVDSII DAVHWLGYSW QNGTGEHLYY 

       130        140        150        160        170        180 
ASDYFEQLYG FAEVLIQRGA AYIDSQSAEQ IAANRGDFTR PGTPSPFRDR SVEENLALFR 

       190        200        210        220        230        240 
DMRAGKYQDG QHVLRARIDM AAPNIVMRDP VLYRIRHAHH HRTGDAWCIY PMYDFTHCIS 

       250        260        270        280        290        300 
DALENITHSL CTLEFENNRP LYDWVLDHLR DAGALPAPLP HQYEFARLHL TYAITSKRKL 

       310        320        330        340        350        360 
LQLVNEKRVD GWDDPRMPTL VGIRRRGYTP ESIQLFCERV GVSKADSWID MSILEAAVRD 

       370        380        390        400        410        420 
DLDARAPRSV AVLDPVKLIL DNVPADFNEP CSAPVHPKQP ELGRREFPLT RELWIEREDF 

       430        440        450        460        470        480 
TETPPKGYFR LFPGNKVRLR YGYVIECTGC DKDADGNITA VHANIIPDTK SGTPGADSVK 

       490        500        510        520        530        540 
VKGNIHWVSA AHALEAEVRL YDRLFTDPQP DSGDKNFLDA LNPDAKRVVT AYLEPTLATA 

       550        560        570        580 
KPEDRFQFER HGYFVADRID SQPGKPVFNR VVGLKDSWGK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646052 Genomic DNA. Translation: CAD14493.1.
RefSeqNP_518912.1. NC_003295.1.

3D structure databases

ProteinModelPortalQ8Y199.
SMRQ8Y199. Positions 15-577.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSc0791.

Proteomic databases

PRIDEQ8Y199.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD14493; CAD14493; RSc0791.
GeneID1219599.
KEGGrso:RSc0791.
PATRIC20260185. VBIRalSol70888_0823.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMASREIYID.
OrthoDBEOG6DRPF7.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-797-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_RALSO
AccessionPrimary (citable) accession number: Q8Y199
Entry history
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries