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Q8Y0L2 (PNCB_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:RSc1031
ORF Names:RS04219
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence caution

The sequence CAD14733.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205840

Sequences

Sequence LengthMass (Da)Tools
Q8Y0L2 [UniParc].

Last modified October 10, 2002. Version 2.
Checksum: 1EA34D69F3CFB74B

FASTA38944,987
        10         20         30         40         50         60 
MIIRSLLDTD LYKFTMMQVV LHHFPGAHVE YRFKCRNPGV DLVPYIEAIR AEIRHLCSLR 

        70         80         90        100        110        120 
FTEAELDYLR GLRFIKSDFV DFLDLFHLSE KYIDIRPAAS NDGQIDIVIS GPWLHTIMFE 

       130        140        150        160        170        180 
VPVLAIVNEV YFSRTQAHPQ WDEGKRRLTE KLASLTRPGL EDCRIADYGT RRRFSHTWHE 

       190        200        210        220        230        240 
HVLMEARSQL GSQYAGTSNV YFAMKHNMTP LGTMAHEYLQ ACQSLGPRLR DSQVFALETW 

       250        260        270        280        290        300 
AREYRGDLGI ALSDTYGFDA FLRDFDMFFC KLFDGVRHDS GDPFEWGERM LKHYEGMRVD 

       310        320        330        340        350        360 
PQSKALIFSD SLDMPKVVRL YERFRSRCKL AFGVGTNLTN DLGYTPLQIV IKMVRCNGQP 

       370        380 
VAKLSDAPEK TMCDDPAYLA YLKQVFGVQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646052 Genomic DNA. Translation: CAD14733.1. Different initiation.
RefSeqNP_519152.1. NC_003295.1.

3D structure databases

ProteinModelPortalQ8Y0L2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSc1031.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD14733; CAD14733; RSc1031.
GeneID1219840.
KEGGrso:RSc1031.
PATRIC20260637. VBIRalSol70888_1048.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-1038-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_RALSO
AccessionPrimary (citable) accession number: Q8Y0L2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 10, 2002
Last modified: March 19, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways