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Q8XYN9 (G6PI_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:RSc1719
ORF Names:RS02909
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length539 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 539539Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180717

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5051 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8XYN9 [UniParc].

Last modified March 27, 2002. Version 1.
Checksum: BF3C9F1FA700BC89

FASTA53958,631
        10         20         30         40         50         60 
MPTALPAWQS LSQHAQAIRA THMRDWFAAP DAEQRVHAFT VEAAGLTLDY AKNRITPETL 

        70         80         90        100        110        120 
ALLLQLADEA GVLTLRDAML RGERINNTEH RSVLHAALRG HAEDDYRANG AAVMPDVLRV 

       130        140        150        160        170        180 
RAQMRDFAQR VHSGTWTGHA GQRITDVVNI GIGGSDLGPR MVCRALAHLA VPQVRVHFVS 

       190        200        210        220        230        240 
NVDGTDLAET LAGLNPDTTL AIVCSKTFTT LETMANAHSM RRWFIEHGVP EAQLKQHFVA 

       250        260        270        280        290        300 
VSTNRDAVVA FGIDPDNMFT FWDWVGGRFS LWSAVGLSIV LAIGPEQFET MLDGARAMDR 

       310        320        330        340        350        360 
HFASAAPREN MPLILGLLSV WYRGFFGAAS ACTVPYCAPL ELLTDFMQQL EMESNGKSVQ 

       370        380        390        400        410        420 
RNGAAIGTDT GPIVWGTAGT NGQHAYFQLI HQGSQIVPVD FITTLEPVRS LPGHHTKLLA 

       430        440        450        460        470        480 
NCFAQGEALL RGRTAEEVRA DGITDAALVP HMVFEGNRPS NTILMQRLDA ASLGALIACA 

       490        500        510        520        530 
EHRTFVQGAV WNINSFDQWG VELGKKLAKP ILEELEGAPA SVAHDASTAA LIRRAKAAR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL646052 Genomic DNA. Translation: CAD15421.1.
RefSeqNP_519840.1. NC_003295.1.

3D structure databases

ProteinModelPortalQ8XYN9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267608.RSc1719.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAD15421; CAD15421; RSc1719.
GeneID1220557.
KEGGrso:RSc1719.
PATRIC20262125. VBIRalSol70888_1763.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMARLKYFAA.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycRSOL267608:GCVU-1754-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RALSO
AccessionPrimary (citable) accession number: Q8XYN9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: March 27, 2002
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways