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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (RSc2137), Glucose-6-phosphate isomerase (pgi)
  3. no protein annotated in this organism
  4. Fructose-1,6-bisphosphate aldolase (fbaA)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei353Proton donorUniRule annotation1
Active sitei384UniRule annotation1
Active sitei505UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciRSOL267608:RS_RS08695-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:RSc1719
ORF Names:RS02909
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
Proteomesi
  • UP000001436 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001807171 – 539Glucose-6-phosphate isomeraseAdd BLAST539

Interactioni

Protein-protein interaction databases

STRINGi267608.RSc1719

Structurei

3D structure databases

ProteinModelPortaliQ8XYN9
SMRiQ8XYN9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiSFIIPDD
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XYN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTALPAWQS LSQHAQAIRA THMRDWFAAP DAEQRVHAFT VEAAGLTLDY
60 70 80 90 100
AKNRITPETL ALLLQLADEA GVLTLRDAML RGERINNTEH RSVLHAALRG
110 120 130 140 150
HAEDDYRANG AAVMPDVLRV RAQMRDFAQR VHSGTWTGHA GQRITDVVNI
160 170 180 190 200
GIGGSDLGPR MVCRALAHLA VPQVRVHFVS NVDGTDLAET LAGLNPDTTL
210 220 230 240 250
AIVCSKTFTT LETMANAHSM RRWFIEHGVP EAQLKQHFVA VSTNRDAVVA
260 270 280 290 300
FGIDPDNMFT FWDWVGGRFS LWSAVGLSIV LAIGPEQFET MLDGARAMDR
310 320 330 340 350
HFASAAPREN MPLILGLLSV WYRGFFGAAS ACTVPYCAPL ELLTDFMQQL
360 370 380 390 400
EMESNGKSVQ RNGAAIGTDT GPIVWGTAGT NGQHAYFQLI HQGSQIVPVD
410 420 430 440 450
FITTLEPVRS LPGHHTKLLA NCFAQGEALL RGRTAEEVRA DGITDAALVP
460 470 480 490 500
HMVFEGNRPS NTILMQRLDA ASLGALIACA EHRTFVQGAV WNINSFDQWG
510 520 530
VELGKKLAKP ILEELEGAPA SVAHDASTAA LIRRAKAAR
Length:539
Mass (Da):58,631
Last modified:March 27, 2002 - v1
Checksum:iBF3C9F1FA700BC89
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA Translation: CAD15421.1
RefSeqiWP_011001658.1, NC_003295.1

Genome annotation databases

EnsemblBacteriaiCAD15421; CAD15421; RSc1719
GeneIDi1220557
KEGGirso:RSc1719
PATRICifig|267608.8.peg.1763

Similar proteinsi

Entry informationi

Entry nameiG6PI_RALSO
AccessioniPrimary (citable) accession number: Q8XYN9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: March 27, 2002
Last modified: June 20, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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