Reviewed, UniProtKB/Swiss-Prot Q8XX54 (DADA2_RALSO)

Names and origin

Protein names

Recommended name:
    D-amino acid dehydrogenase 2 small subunit
    EC=1.4.99.1

Gene names

Name:	dadA2
Ordered Locus Names:	RSc2262
ORF Names:	RS01297

Organism

Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity.
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity.
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the dadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 425	425	D-amino acid dehydrogenase 2 small subunit HAMAP MF_01202		PRO_0000166144
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8XX54-1 [UniParc]. Last modified March 5, 2002. Version 1. Checksum: 0723B56E5B752CA6	FASTA	425	44,455
	10 20 30 40 50 60 MQITVVGAGI VGISTAYALA QEGHQVTLVE RNPGPGEGTS YANGGQLSYS YVAPLAGPGV 70 80 90 100 110 120 LSHVPGWLLR RDSPLRLKPS LDPVLLRWGL RFIAACNRER ADRTTRELLA LSFYSRARME 130 140 150 160 170 180 ALRAASPDLS FSFARRGKLV VYRDAAAFAS ARAQVGYQAT LGCEQHALSA DETIAREPAL 190 200 210 220 230 240 AGARGAIVGA IYTPDEDVAD CHQLCVGLFN RLCALPNVAL RFNAGAESLW VEGRRVRGVR 250 260 270 280 290 300 TAHEPITADA VVVAAGVASA GLLGPLRIDP GLYPLKGYSI SLPLGEGGAG SDGAPVVSVT 310 320 330 340 350 360 DAARKIVYAR IGRTLRVAGM ADLVGWSDRL DPRRVQTLYD ETRALFPAAL RASDAGADAA 370 380 390 400 410 420 PWAGMRPATP TGVPVVGPSP VDGLWLNVGH GALGFTLAMG SAGLLADLIA RRAPAIAAAP YALAR

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL646052 Genomic DNA. Translation: CAD15969.1.
RefSeq	NP_520383.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1221107.
GenomeReviews	Gene locus RSc2262 in contig AL646052_GR.
KEGG	rso:RSc2262.
NMPDR	fig|267608.1.peg.2262.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8XX54.
OMA	Q8XX54. TLAMGSA.
Enzyme and pathway databases
BioCyc	RSOL267608:RSC2262-MON.
BRENDA	1.4.99.1. 97066.
Family and domain databases
HAMAP	MF_01202. [Tree]
InterPro	IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

DADA2_RALSO

Accession

Primary (citable) accession number: Q8XX54

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	March 5, 2002
Last modified:	May 5, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)