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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [glutamine synthetase]-L-tyrosine = diphosphate + [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:RSc2656
ORF Names:RS04556
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
Proteomesi
  • UP000001436 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002092701 – 955Glutamate-ammonia-ligase adenylyltransferaseAdd BLAST955

Interactioni

Protein-protein interaction databases

STRINGi267608.RSc2656.

Structurei

3D structure databases

ProteinModelPortaliQ8XW19.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni88 – 304GlnE 1Add BLAST217
Regioni624 – 832GlnE 2Add BLAST209

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8XW19-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAQAPLSVA PFLQTPACPS EAPGAVLPFS LNYSRYVQRL AQARAGWAER
60 70 80 90 100
VQAAAAGPIS VAWLSARFGE LFEAAAAEPE QALKRALRLL RNEVFAALAE
110 120 130 140 150
RDLSGAATLD EVTGAMTDFA EFAVRAAIAV IGQELGALHG QPVGQSSGEV
160 170 180 190 200
QELVVVGMGK LGGRELNVSS DIDLIFLYDE EGDTQGGPRP LSNHEYFTKL
210 220 230 240 250
GRRLINALAD VTEDGYVFRV DMRLRPNGDA GPLACSLGML EEYFVVQGRE
260 270 280 290 300
WERYAWIKGR VITDPGSPHA ARVIQQLERV TTPFVFRRYL DYGVIAAIRA
310 320 330 340 350
LHAQIRAEAA KRSNAANRQH GGHDSQVQAH APNIKLGRGG IREIEFVAQV
360 370 380 390 400
FQLIRGGQDF GLRIRPTLEV LRAAAERGLI GADAVARLTD AYRFLRQLEH
410 420 430 440 450
RLQYVDDAQT HNLPGAPEDQ LRIARMMGFA DYAALVAQLE RYQDEVAQQF
460 470 480 490 500
EQTFSDKQDN QPPCAAIWHA DLLDDERTES ARAQLLELGY ADADSVLERL
510 520 530 540 550
RASRHSPRYR ALSEVSRQRF DLLINRALDH AARQTDADVT IARFLDFFDA
560 570 580 590 600
ISRRSSYLSL LSEYPQAMAR VAHTLHASRW AADYLTRHPQ LLDELLDTEA
610 620 630 640 650
LSAAPDWQGF RERVRERLRA AGDHVEMQMD ILRQEHHAET FRILLQDLQG
660 670 680 690 700
MLTVEPISDR LSDLADAVLD LTLETVWQQV STRHREVPRF AVVAYGRLGG
710 720 730 740 750
KELGYASDLD LIFLYDDDDE RAPEVYAAYA RKLITWLTSH TAAGMLFDVD
760 770 780 790 800
TRLRPNGAAG LMVTHFEAFR RYQMREGDNA AWVWEHQALT RARFCAGDPE
810 820 830 840 850
IGARFEALRI AVLRQPREAG PLRDEIAAMR ERVLEGHANP TPLFDLKHDR
860 870 880 890 900
GGMVDIEFTV QFLVLLHSAA YAELTRNAGN IALLRMAGEL GLIDAARAAR
910 920 930 940 950
VADAYRDFRA RQHKLRLDGQ SAARVPAGTC AHEAAHVRAL WEQVFGSIDA

ASPTP
Length:955
Mass (Da):106,370
Last modified:March 1, 2002 - v1
Checksum:i78037681294C581A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA. Translation: CAD16363.1.
RefSeqiWP_011002566.1. NC_003295.1.

Genome annotation databases

EnsemblBacteriaiCAD16363; CAD16363; RSc2656.
GeneIDi1221503.
KEGGirso:RSc2656.
PATRICi20264017. VBIRalSol70888_2700.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646052 Genomic DNA. Translation: CAD16363.1.
RefSeqiWP_011002566.1. NC_003295.1.

3D structure databases

ProteinModelPortaliQ8XW19.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267608.RSc2656.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD16363; CAD16363; RSc2656.
GeneIDi1221503.
KEGGirso:RSc2656.
PATRICi20264017. VBIRalSol70888_2700.

Phylogenomic databases

eggNOGiENOG4105CE6. Bacteria.
COG1391. LUCA.
HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.
OrthoDBiPOG091H0675.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_RALSO
AccessioniPrimary (citable) accession number: Q8XW19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: March 1, 2002
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.