Reviewed, UniProtKB/Swiss-Prot Q8XVQ0 (UBIC_RALSO)

Names and origin

Protein names

Recommended name:
    Probable chorismate--pyruvate lyase
      Short name=CL
      Short name=CPL
    EC=4.1.3.40

Gene names

Name:	ubiC
Ordered Locus Names:	RSc2780

Organism

Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	195 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity.
Catalytic activity	Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the ubiC family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Cellular component	Cytoplasm
Ligand	Pyruvate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyruvate biosynthetic process Inferred from electronic annotation. Source: HAMAP ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chorismate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 195	195	Probable chorismate--pyruvate lyase HAMAP MF_01632		PRO_0000240567
Sites
	Binding site	79	1	Substrate By similarity
	Binding site	117	1	Substrate; via amide nitrogen By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8XVQ0-1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: 43739623F6DF1F33	FASTA	195	21,202
	10 20 30 40 50 60 MSGAAMSYPR SPWRGALPPM AVYGQHWARW AVGVNSLTAR LRAASSSFRV ELLGQGRALP 70 80 90 100 110 120 LRDEWRCLGL PRAAETLARE VLLICDEAPV VYAHTIVHPR SVAADWPFLR ALGTQPLGHA 130 140 150 160 170 180 LFADPRVARG AFEFALLDGR HPLVKRAHAA LGGTPPGAMA RLPARRSVFR RGVSAMLVTE 190 VFLPALAVFD PPPMM

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL646052 Genomic DNA. Translation: CAD16487.1. Different initiation.
3D structure databases
ModBase	Search...
Genome annotation databases
GenomeReviews	Gene locus RSc2780 in contig AL646052_GR.
KEGG	rso:RSc2780.
NMPDR	fig|267608.1.peg.2780.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8XVQ0.
Enzyme and pathway databases
BioCyc	RSOL267608:RSC2780-MON.
BRENDA	4.1.3.40. 97066.
Family and domain databases
HAMAP	MF_01632. [Tree]
InterPro	IPR007440. Chorismate--pyruvate_lyase. [Graphical view]
Pfam	PF04345. Chor_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UBIC_RALSO

Accession

Primary (citable) accession number: Q8XVQ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	June 26, 2007
Last modified:	September 22, 2009
This is version 36 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)