Reviewed, UniProtKB/Swiss-Prot Q8XVE6 (TRPC1_RALSO)

Names and origin

Protein names

Recommended name:
    Indole-3-glycerol phosphate synthase 1
      Short name=IGPS 1
    EC=4.1.1.48

Gene names

Name:	trpC1
Ordered Locus Names:	RSc2885
ORF Names:	RS00217

Organism

Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the trpC family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 267	267	Indole-3-glycerol phosphate synthase 1 HAMAP MF_00134		PRO_0000154242

Sequences

	Sequence		Length	Mass (Da)
	Q8XVE6-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 72FFC374AB655F24	FASTA	267	29,141
	10 20 30 40 50 60 MSDILQKILA VKAEEVAAAR KHRDLPSVRA EAEANRHDST LGPRGFAQAL RDKIGAGRAA 70 80 90 100 110 120 VIAEVKKASP SKGVLRPDFK PAEIAGSYAE HGAACLSVLT DEQFFQGHAD YLREARAACA 130 140 150 160 170 180 LPALRKDFMV DLYQVYEARS WGADCILLIV SALDQGLMAE LEACAHELGM DVLVEVHDGH 190 200 210 220 230 240 ELERALRLST PLVGVNNRNL RTFETTLDTT LGLLKHMPDD RIVVTESGIL KPDDVRKMRA 250 260 ADVNAFLVGE AFMRADDPGT ELARLFA

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL646052 Genomic DNA. Translation: CAD16592.1.
RefSeq	NP_521006.1.
3D structure databases
HSSP	HSSP built from PDB template 1PII based on UniProtKB P00909.
ModBase	Search...
Genome annotation databases
GeneID	1221738.
GenomeReviews	Gene locus RSc2885 in contig AL646052_GR.
KEGG	rso:RSc2885.
NMPDR	fig|267608.1.peg.2885.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8XVE6.
OMA	PLLCKDF.
Enzyme and pathway databases
BioCyc	RSOL267608:RSC2885-MON.
BRENDA	4.1.1.48. 97066.
Family and domain databases
HAMAP	MF_00134. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GPS_central. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
ProDom	PD001511. IGPS. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPC1_RALSO

Accession

Primary (citable) accession number: Q8XVE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2002
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)