ID   GLGA_RALN1              Reviewed;         541 AA.
AC   Q8XT73;
DT   10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   RecName: Full=Glycogen synthase {ECO:0000255|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000255|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000255|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000255|HAMAP-Rule:MF_00484};
GN   OrderedLocusNames=RSp0242; ORFNames=RS03725;
OS   Ralstonia nicotianae (strain GMI1000) (Ralstonia solanacearum).
OG   Plasmid megaplasmid Rsp.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-
CC         alpha-D-glucosyl](n+1) + ADP + H(+); Xref=Rhea:RHEA:18189, Rhea:RHEA-
CC         COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC         ChEBI:CHEBI:57498, ChEBI:CHEBI:456216; EC=2.4.1.21;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000255|HAMAP-
CC       Rule:MF_00484}.
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DR   EMBL; AL646053; CAD17393.1; -; Genomic_DNA.
DR   RefSeq; WP_011003556.1; NC_003296.1.
DR   AlphaFoldDB; Q8XT73; -.
DR   SMR; Q8XT73; -.
DR   STRING; 267608.RSp0242; -.
DR   CAZy; GT5; Glycosyltransferase Family 5.
DR   EnsemblBacteria; CAD17393; CAD17393; RSp0242.
DR   GeneID; 60503179; -.
DR   KEGG; rso:RSp0242; -.
DR   PATRIC; fig|267608.8.peg.3711; -.
DR   eggNOG; COG0297; Bacteria.
DR   HOGENOM; CLU_009583_18_4_4; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd03791; GT5_Glycogen_synthase_DULL1-like; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   NCBIfam; TIGR02095; glgA; 1.
DR   PANTHER; PTHR45825; GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC; 1.
DR   PANTHER; PTHR45825:SF11; STARCH SYNTHASE 1, CHLOROPLASTIC_AMYLOPLASTIC; 1.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Glycogen biosynthesis; Glycosyltransferase; Plasmid; Transferase.
FT   CHAIN           1..541
FT                   /note="Glycogen synthase"
FT                   /id="PRO_0000188635"
FT   REGION          497..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         17
FT                   /ligand="ADP-alpha-D-glucose"
FT                   /ligand_id="ChEBI:CHEBI:57498"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00484"
SQ   SEQUENCE   541 AA;  57983 MW;  6CF523CB26649FDB CRC64;
     MSLNVLFVAS EAVPLAKTGG LGDMVGACAG ALQRAGLHVT VMLPGYPAAQ AQLRDARVAC
     ALPDLPGGPA RVLLGAMPDT GVPVLLLDAP ALFDRPGNPY LDACGEPYAD NALRFAAFSH
     AAAHVAGGVP DLPAFDIVQA HDWHAALVPL LVKRAGRPVK TVLTVHNLAF QGNFPPRIAQ
     DLGLPPEAVR EAGFFGQFSF LKAGLMWADR ITTVSRTYAR EILTDAFGYG MQDVLRARRH
     DLVAILNGID NAVWNPSKDA YLSRPFFAGN LSGKHAAKLQ LQTLLRLPKD AHAPLLALGS
     RLTHQKMADV ALQALPQMLE AHPDLQVAVL GCGERRYESA MAALAERHPR RMAAVIGYTE
     RNAHMLHAGA DLLLHGSRFE PCGLTPLYAM RYGTVPVASR VGGLVDTIAD RGSPEAALRG
     ATGFLFDGET PEAMAGAVAR ALRVFVQPRA WRVLQYNGMT TDFGWSQPAS EYLALYATLA
     PRATPMPHLQ HWPMRTLARP ASPPDTAPVG KPARRRRTTA LSTTARAHPV ARAAGREKIR
     A
//