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Q8XT38 (TREA_RALSO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Periplasmic trehalase
EC=3.2.1.28
Alternative name(s):
Alpha,alpha-trehalase
Alpha,alpha-trehalose glucohydrolase
Gene names
Name:treA
Ordered Locus Names:RSp0277
ORF Names:RS03687
Encoded onPlasmid megaplasmid Rsp
OrganismRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum) [Complete proteome] [HAMAP]
Taxonomic identifier267608 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system By similarity. HAMAP MF_01060

Catalytic activity

Alpha,alpha-trehalose + H2O = 2 D-glucose. HAMAP MF_01060

Subcellular location

Periplasm By similarity HAMAP MF_01060.

Sequence similarities

Belongs to the glycosyl hydrolase 37 family.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Plasmid
Gene Ontology (GO)
   Biological processcellular hyperosmotic response

Inferred from electronic annotation. Source: InterPro

trehalose catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionalpha,alpha-trehalase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 4545 Potential
Chain46 – 551506Periplasmic trehalase HAMAP MF_01060
PRO_0000012045

Sequences

Sequence LengthMass (Da)Tools
Q8XT38 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: AE9AD74F51853274

FASTA55160,733
        10         20         30         40         50         60 
MLDPRGLARP SRFCPRIIYA GTSHIRRATA AALLAASLCA LPACADVGVG AALPLSPDKL 

        70         80         90        100        110        120 
YGELFVAVQT AQVYPDQKTF VDTVPKADPA VILQAYRAQK DVPGFSLKAF VDQYFTVPFE 

       130        140        150        160        170        180 
TVITPPAGQS LRAHINWLWP ALTRTTATAP DNSSLIPLPK PYVVPGGRFR EVYYWDTYFT 

       190        200        210        220        230        240 
MLGLQASGRD DLVDSMLDNF AYQINRFGHI PNGNRTYYLS RSQPPFFALM VELAATKEGE 

       250        260        270        280        290        300 
AAYTRYLAPL RKEYAYWMRG AAGTAPGQAS GNVVVLPDGT VLNRYWDDEA TPRPESYLQD 

       310        320        330        340        350        360 
VATAQQAPDR PAAEVWRDLR AAAESGWDFS SRWFGDSATL ATIRTTSILP VDLNALMFQL 

       370        380        390        400        410        420 
EKTIAKGCAV ARDFACTVEF GNHARKRAVA VERYLWHPAG YYADYDWKLG KVRDNLSAAA 

       430        440        450        460        470        480 
TYPLFVQMAP WGRARQTLRQ TQTALLQVGG LSTTTLHTQQ QWDAPNGWAP LQWIALQASQ 

       490        500        510        520        530        540 
HYGQALLAQT IGERFLGSVE RLYAAEQKLV EKYIVDGSGT GGGGGEYPLQ DGFGWTNGVT 

       550 
LRLLDAYGRG Q

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL646053 Genomic DNA. Translation: CAD17428.1.
RefSeqNP_521838.1. NC_003296.1.

3D structure databases

ProteinModelPortalQ8XT38.
SMRQ8XT38. Positions 54-549.
ModBaseSearch...

Protein family/group databases

CAZyGH37. Glycoside Hydrolase Family 37.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1222409.
GenomeReviewsGene locus RSp0277 in contig AL646053_GR.
KEGGrso:RSp0277.
NMPDRfig|267608.1.peg.3717.
PATRIC20266149. VBIRalSol70888_3746.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG485982.
OMANRYWDAS.
ProtClustDBCLSK897717.

Enzyme and pathway databases

BioCycRSOL267608:RSP0277-MONOMER.

Family and domain databases

HAMAPMF_01060. Peripl_trehalase.
[Tree]
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR001661. Glyco_hydro_37.
IPR018232. Glyco_hydro_37_CS.
IPR023720. Trehalase_periplasmic.
[Graphical view]
KOK01194.
PANTHERPTHR23403. Glyco_hydro_37. 1 hit.
PfamPF01204. Trehalase. 1 hit.
[Graphical view]
PRINTSPR00744. GLHYDRLASE37.
SUPFAMSSF48208. Glyco_trans_6hp. 1 hit.
PROSITEPS00927. TREHALASE_1. 1 hit.
PS00928. TREHALASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTREA_RALSO
AccessionPrimary (citable) accession number: Q8XT38
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

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