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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. Cobyrinate a,c-diamide synthase (cbiA)
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciRSOL267608:G1G1H-4319-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:RSp0622
ORF Names:RS03745
Encoded oniPlasmid megaplasmid Rsp0 Publication
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
Proteomesi
  • UP000001436 Componenti: Plasmid megaplasmid Rsp

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001416811 – 383Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST383

Structurei

3D structure databases

ProteinModelPortaliQ8XS59
SMRiQ8XS59
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XS59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPSARRPFD LATPAPNGLR RGRTTGTCAT AAVKAALLRL VRGETVDAVE
60 70 80 90 100
VSLPDPDYCL EVPIARIEPL ASGAVRADVL KYAGDDPDNT DGATIFAEVS
110 120 130 140 150
VNHAGEVRFM AAPGVGTVTQ PGLRVPPGEP AINPVPRQMM RMAVDEVLAG
160 170 180 190 200
GANPGFDLAI GCVDGERIAR RTFNPMLGIV GGISILGTSG IVEPMSLAAW
210 220 230 240 250
MASIEVYVRV ALGDAPEAIA FTPGKIGRAY AAHPLALSKK QVVQIANFIG
260 270 280 290 300
ASLDYAQTAL EEDRHRLGTL WVLGHPGKLA KVLDGVWDTH SSKSGMAMGS
310 320 330 340 350
VAAVAAELGV AAALVEQIKT ANTVENVIQI LQHQPGAQAF WTEIEQRIAA
360 370 380
RMQPRVPRAD RVAVRLFAMD GTPLGAAGQE AGA
Length:383
Mass (Da):40,107
Last modified:March 1, 2002 - v1
Checksum:iB9508D5FFC7100E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646053 Genomic DNA Translation: CAD17773.1
RefSeqiWP_011003920.1, NC_003296.1

Genome annotation databases

EnsemblBacteriaiCAD17773; CAD17773; RSp0622
GeneIDi1222929
KEGGirso:RSp0622
PATRICifig|267608.8.peg.4092

Similar proteinsi

Entry informationi

Entry nameiCBID_RALSO
AccessioniPrimary (citable) accession number: Q8XS59
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

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