Reviewed, UniProtKB/Swiss-Prot Q8XS01 (TRPC2_RALSO)

Names and origin

Protein names

Recommended name:
    Indole-3-glycerol phosphate synthase 2
      Short name=IGPS 2
    EC=4.1.1.48

Gene names

Name:	trpC2
Ordered Locus Names:	RSp0680
ORF Names:	RS01769

Encoded on

Plasmid megaplasmid Rsp

Organism

Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP]

Taxonomic identifier

305 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the trpC family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 268	268	Indole-3-glycerol phosphate synthase 2 HAMAP MF_00134		PRO_0000154243

Sequences

	Sequence		Length	Mass (Da)
	Q8XS01-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 7E4BD95DDA2FE151	FASTA	268	28,757
	10 20 30 40 50 60 MGILDAIKLG KEKEVAHAKT VRKLSGLEQA IKQRPPPRDF VGAVAERAGN GTVALIAEIK 70 80 90 100 110 120 KASPSKGLIR SDFQVAAIAE AYRDGGAACL SVLTDQTFFQ GKPADLELAK AVSGLPVLRK 130 140 150 160 170 180 DFMIDPYQVH EARAMGADAI LLILAMLDHG QAIELEAAAQ AMGMGVLIEI HDEPELERAM 190 200 210 220 230 240 AMQSRLIGIN NRDLATFAAD LTTSERLASK VDRNRIVISE SGIGGHGDVI RLMEAGINGF 250 260 LIGEQLLRAR HIESATREIA QARLHACP

References

[1]

"Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. , Robert C., Saurin W., Schiex T., Siguier P., Thebault P., Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A. Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL646053 Genomic DNA. Translation: CAD17831.1.
RefSeq	NP_522241.1.
3D structure databases
HSSP	HSSP built from PDB template 1JCM based on UniProtKB P00909.
ModBase	Search...
Genome annotation databases
GeneID	1222987.
GenomeReviews	Gene locus RSp0680 in contig AL646053_GR.
KEGG	rso:RSp0680.
NMPDR	fig|267608.1.peg.4120.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8XS01.
OMA	LYPSAIN.
Enzyme and pathway databases
BioCyc	RSOL267608:RSP0680-MON.
BRENDA	4.1.1.48. 97066.
Family and domain databases
HAMAP	MF_00134. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GPS_central. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
ProDom	PD001511. IGPS. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPC2_RALSO

Accession

Primary (citable) accession number: Q8XS01

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2002
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)