Q8XRN1 (DNAE2_RALSO)
Reviewed,
UniProtKB/Swiss-Prot
Last modified
August 10, 2010.
Version 55.
History...
Names and origin
| Protein names | Recommended name: Error-prone DNA polymerase EC=2.7.7.7 | ||||||
| Gene names |
| ||||||
| Encoded on | Plasmid megaplasmid Rsp | ||||||
| Organism | Ralstonia solanacearum (Pseudomonas solanacearum) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 305 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia |
Protein attributes
| Sequence length | 1075 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902 |
| Catalytic activity | Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_01902. |
| Sequence similarities | Belongs to the DNA polymerase type-C family. DnaE2 subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | DNA damage DNA repair DNA replication |
| Cellular component | Cytoplasm |
| Molecular function | DNA-directed DNA polymerase Nucleotidyltransferase Transferase |
| Technical term | Complete proteome Plasmid |
| Gene Ontology (GO) | |
| Biological process | DNA repair Inferred from electronic annotation. Source: UniProtKB-KW DNA replicationInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA bindingInferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 1075 | 1075 | Error-prone DNA polymerase HAMAP MF_01902 | PRO_0000103393 | |||
Sequences
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References
| [1] | "Genome sequence of the plant pathogen Ralstonia solanacearum." Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M., Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M., Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M., Moisan A. Boucher C.A.Nature 415:497-502(2002) [PubMed: 11823852] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GMI1000. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AL646053 Genomic DNA. Translation: CAD17951.1. |
| RefSeq | NP_522361.1. |
3D structure databases | |
| ProteinModelPortal | Q8XRN1. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1223107. |
| GenomeReviews | Gene locus RSp0800 in contig AL646053_GR. |
| KEGG | rso:RSp0800. |
| NMPDR | fig|267608.1.peg.4240. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG734490. |
| OMA | SCILTEA. |
| ProtClustDB | PRK05672. |
Enzyme and pathway databases | |
| BioCyc | RSOL267608:RSP0800-MONOMER. |
| BRENDA | 2.7.7.7. 97066. |
Family and domain databases | |
| HAMAP | MF_01902. DNApol_error_prone. [Tree] |
| InterPro | IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view] |
| Pfam | PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view] |
| SMART | SM00481. POLIIIAc. 1 hit. [Graphical view] |
| SUPFAM | SSF89550. PHP-like. 1 hit. |
| TIGRFAMs | TIGR00594. polc. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | DNAE2_RALSO | ||||||||
| Accession | Primary (citable) accession number: Q8XRN1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with


