Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8XRG0

- ACDH_RALSO

UniProt

Q8XRG0 - ACDH_RALSO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acetaldehyde dehydrogenase

Gene

dmpF

Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD+ and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.UniRule annotation

Catalytic activityi

Acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei130 – 1301Acyl-thioester intermediateUniRule annotation
Binding sitei284 – 2841NADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 154NADUniRule annotation
Nucleotide bindingi161 – 1699NADUniRule annotation

GO - Molecular functioni

  1. acetaldehyde dehydrogenase (acetylating) activity Source: UniProtKB-HAMAP
  2. NAD binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic compound catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRSOL267608:GCVU-4398-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetaldehyde dehydrogenaseUniRule annotation (EC:1.2.1.10UniRule annotation)
Alternative name(s):
Acetaldehyde dehydrogenase [acetylating]UniRule annotation
Gene namesi
Name:dmpF
Ordered Locus Names:RSp0894
Encoded oniPlasmid megaplasmid Rsp0 Publication
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000001436: Plasmid megaplasmid Rsp

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Acetaldehyde dehydrogenasePRO_0000387717Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267608.RS01665.

Structurei

3D structure databases

ProteinModelPortaliQ8XRG0.
SMRiQ8XRG0. Positions 1-306.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the acetaldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG4569.
KOiK04073.
OMAiHQGNVNM.
OrthoDBiEOG6H1PXH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01657. Ac_ald_DH_ac.
InterProiIPR003361. Acetaldehyde_dehydrogenase.
IPR015426. Acetylaldehyde_DH_C.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view]
PfamiPF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view]
PIRSFiPIRSF015689. Actaldh_dh_actl. 1 hit.
SMARTiSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03215. ac_ald_DH_ac. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8XRG0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRKLKVAII GSGNIGTDLM IKVLRHGGPI EMGAMVGIDP GSDGLARAAR
60 70 80 90 100
LGVPTTAEGL EGLLRLPGFK DIGLVFDATS AGAHHRHAAR LAELGVPMID
110 120 130 140 150
LTPAAIGPYV VPVVNGEAHR GARNINMVTC GGQATIPIVA AVSQVARVHY
160 170 180 190 200
AEIVASIASR SAGPGTRANI DEFTETTSRA IEAVGGAERG KAIIILNPAE
210 220 230 240 250
PPLMMRDTVF TFSAPASESE VEASIEAMVA KVQAYVSGYR LKQRVQFEHT
260 270 280 290 300
EVALPGAGRV RGLKTTVLLE VRGAAHYLPE YAGNLDIMTS AALACAQAQA

AALIAA
Length:306
Mass (Da):31,755
Last modified:March 1, 2002 - v1
Checksum:i8B911F98541F371B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646053 Genomic DNA. Translation: CAD18045.1.
RefSeqiNP_522455.1. NC_003296.1.

Genome annotation databases

EnsemblBacteriaiCAD18045; CAD18045; RSp0894.
GeneIDi1223201.
KEGGirso:RS01665.
PATRICi20267395. VBIRalSol70888_4370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL646053 Genomic DNA. Translation: CAD18045.1 .
RefSeqi NP_522455.1. NC_003296.1.

3D structure databases

ProteinModelPortali Q8XRG0.
SMRi Q8XRG0. Positions 1-306.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 267608.RS01665.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD18045 ; CAD18045 ; RSp0894 .
GeneIDi 1223201.
KEGGi rso:RS01665.
PATRICi 20267395. VBIRalSol70888_4370.

Phylogenomic databases

eggNOGi COG4569.
KOi K04073.
OMAi HQGNVNM.
OrthoDBi EOG6H1PXH.

Enzyme and pathway databases

BioCyci RSOL267608:GCVU-4398-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_01657. Ac_ald_DH_ac.
InterProi IPR003361. Acetaldehyde_dehydrogenase.
IPR015426. Acetylaldehyde_DH_C.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view ]
Pfami PF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view ]
PIRSFi PIRSF015689. Actaldh_dh_actl. 1 hit.
SMARTi SM00859. Semialdhyde_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03215. ac_ald_DH_ac. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GMI1000.

Entry informationi

Entry nameiACDH_RALSO
AccessioniPrimary (citable) accession number: Q8XRG0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3