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Q8XQS6

- GLSA_RALSO

UniProt

Q8XQS6 - GLSA_RALSO

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Protein

Glutaminase

Gene
glsA, RSp1143, RS05469
Organism
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei113 – 1131Substrate By similarity
Binding sitei157 – 1571Substrate By similarity
Binding sitei164 – 1641Substrate By similarity
Binding sitei188 – 1881Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciRSOL267608:GCVU-4652-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:RSp1143
ORF Names:RS05469
Encoded oniPlasmid megaplasmid Rsp0 Publication
OrganismiRalstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
Taxonomic identifieri267608 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia
ProteomesiUP000001436: Plasmid megaplasmid Rsp

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotationPRO_0000110618Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi267608.RSp1143.

Structurei

3D structure databases

ProteinModelPortaliQ8XQS6.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQRARRIN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8XQS6-1 [UniParc]FASTAAdd to Basket

« Hide

MDYQAILETI HRDIQPWLGK GRVADYIPEL AKASATDFGM AIVTPRGEVF    50
RVGQAETLFS IQSISKLFAC TLAFQLEGES LWQRVGREPS GNAFNSLVQL 100
EHENGIPRNP FINAGALVVT DVLCRRFVQA ETAMVQFMRR LVDNPRVDYN 150
PRVALSELEH ADRNRAMAHF MRSFGNLHMP VETVIDAYCR QCAIEMHCVD 200
LARAVLFLAN GGVVPWSGER VIETSPAKRL SALMLTCGTY DAAGDFVYRV 250
GLPAKSGVGG GIVAVLPGEF GVCVWSPGLD VSGNSLAGLQ ALEWLTTLSG 300
RSIF 304
Length:304
Mass (Da):33,262
Last modified:March 1, 2002 - v1
Checksum:i03B1D8BBF4AC88B9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL646053 Genomic DNA. Translation: CAD18294.1.
RefSeqiNP_522704.1. NC_003296.1.
WP_011004432.1. NC_003296.1.

Genome annotation databases

EnsemblBacteriaiCAD18294; CAD18294; RSp1143.
GeneIDi1223455.
KEGGirso:RSp1143.
PATRICi20267923. VBIRalSol70888_4629.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL646053 Genomic DNA. Translation: CAD18294.1 .
RefSeqi NP_522704.1. NC_003296.1.
WP_011004432.1. NC_003296.1.

3D structure databases

ProteinModelPortali Q8XQS6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 267608.RSp1143.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAD18294 ; CAD18294 ; RSp1143 .
GeneIDi 1223455.
KEGGi rso:RSp1143.
PATRICi 20267923. VBIRalSol70888_4629.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QRARRIN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci RSOL267608:GCVU-4652-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GMI1000.

Entry informationi

Entry nameiGLSA_RALSO
AccessioniPrimary (citable) accession number: Q8XQS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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