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Protein

Uronate isomerase

Gene

uxaC

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciCPER195102:GJFM-177-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:CPE0152
OrganismiClostridium perfringens (strain 13 / Type A)
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000818 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 466466Uronate isomerasePRO_0000172768Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ8XP14.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8XP14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKFMDKDFL LENEVAKVLY HNYASKVPVF DYHCHLVPME IATDHKFKNL
60 70 80 90 100
TEMWLYHDHY KWRAMRSFGI DEEYITGNAS DYDKFYQFAK MMPYLIGNPI
110 120 130 140 150
YHWSHLELKR FFGVEETLSE KTASTIWEKC NKVIENNNLT AKKLIEMANV
160 170 180 190 200
VYIGTTDDPI DDLRYHKQLK EDINFKCSVN PSFRPEKAMK IQNEGFKEYI
210 220 230 240 250
GKLAEVSNVE IKSFDDLKKA LEIRLDYFYE NGCMITDHSL ERVVFYKFSC
260 270 280 290 300
EEINEIFIKA LNGENINNEE ASKYSVALLI SLGKMYAERN MVMQLHIGAL
310 320 330 340 350
RNNNTRMFNR IGADAGFDSI DDGEIAYSLS RILDELDKED KLPKTILYCL
360 370 380 390 400
NPKDNEVLGT MIGNFQGGNI AGKIQFGSGW WFNDQKDGME RQMMALSQLG
410 420 430 440 450
LISQFVGMVT DSRSFLSYTR HEYFRRILCN YLGNLVESGQ YPYEEEILGE
460
IVQNICYKNS AKYFKR
Length:466
Mass (Da):54,441
Last modified:March 1, 2002 - v1
Checksum:i25ECEA6E5C201897
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA. Translation: BAB79858.1.
RefSeqiWP_011009640.1. NC_003366.1.

Genome annotation databases

EnsemblBacteriaiBAB79858; BAB79858; BAB79858.
GeneIDi988393.
KEGGicpe:CPE0152.
PATRICi19494186. VBICloPer59675_0210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA. Translation: BAB79858.1.
RefSeqiWP_011009640.1. NC_003366.1.

3D structure databases

ProteinModelPortaliQ8XP14.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB79858; BAB79858; BAB79858.
GeneIDi988393.
KEGGicpe:CPE0152.
PATRICi19494186. VBICloPer59675_0210.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiMAWAKTV.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciCPER195102:GJFM-177-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 13 / Type A.

Entry informationi

Entry nameiUXAC_CLOPE
AccessioniPrimary (citable) accession number: Q8XP14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: March 1, 2002
Last modified: November 11, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.