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Q8XNI1

- UVRC_CLOPE

UniProt

Q8XNI1 - UVRC_CLOPE

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Protein
UvrABC system protein C
Gene
uvrC, CPE0352
Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. SOS response Source: UniProtKB-HAMAP
  2. nucleotide-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nuclease

Keywords - Biological processi

DNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciCPER195102:GJFM-389-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein C
Short name:
Protein UvrC
Alternative name(s):
Excinuclease ABC subunit C
Gene namesi
Name:uvrC
Ordered Locus Names:CPE0352
OrganismiClostridium perfringens (strain 13 / Type A)
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000818: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 620620UvrABC system protein CUniRule annotation
PRO_0000138298Add
BLAST

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex By similarity.

Protein-protein interaction databases

STRINGi195102.CPE0352.

Structurei

3D structure databases

ProteinModelPortaliQ8XNI1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 9280GIY-YIG
Add
BLAST
Domaini204 – 23936UVR
Add
BLAST

Sequence similaritiesi

Belongs to the UvrC family.
Contains 1 GIY-YIG domain.
Contains 1 UVR domain.

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279960.
KOiK03703.
OMAiHRFVITF.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8XNI1-1 [UniParc]FASTAAdd to Basket

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MFDFQHQLKI LPDKPGVYIM KNSLGEVIYV GKAKVLKNRV RQYFQNSKNH    50
SEKVRAMVKN IAEFEYIVTD SEMEALILEC NLIKKYSPRY NIALKDDKFY 100
PFIKITTNED FPRVYVTRNF AKDGNRYFGP YTNGTAVYEV MGLIKKLFPL 150
RTCKKAIVEG GEPTRACLNY HINLCKAPCA GYISKAEYWE MIDEIINILN 200
GTDTSIIKKL KLEMEKAAEE LEFEKAAKIR DRILAIELIS EKQKMFTVKE 250
GDEDFIDLYT DEKDGCAQVF FVREGKVTGR EHFMIENIGD DPVKEVISSF 300
IASFYGGTAQ IPKTIYVPEE IEDQELIEKF LTEKRGSKVW IKVPKKGDKK 350
NLLDMVRNNA KIMLDQFKEK MVEEKELNKS ALTELADVLG LDSLPVRIEA 400
YDISNIQGVD SVGTMVVFEN GKAKNSDYRR FKIKSVKGPN DYESMREILS 450
RRFSHGLEEV NKIKERNLEY SNGKFCIFPD LIMMDGGKGQ VNIALEVLKG 500
FGIEIPVCGL VKDHKHRTRG IILNNEEILI RRGSGLMNLI TRVQDEVHRY 550
AITYHRSLRD KRTLHSILED IPRIGEKRRR NLLMKFGSID NIKKASMEEL 600
LDTPGIDKRA AESIKQYFSS 620
Length:620
Mass (Da):71,391
Last modified:March 1, 2002 - v1
Checksum:i6ED4ADE9C3849219
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000016 Genomic DNA. Translation: BAB80058.1.
RefSeqiNP_561268.1. NC_003366.1.
WP_011009760.1. NC_003366.1.

Genome annotation databases

EnsemblBacteriaiBAB80058; BAB80058; BAB80058.
GeneIDi988605.
KEGGicpe:CPE0352.
PATRICi19494610. VBICloPer59675_0410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000016 Genomic DNA. Translation: BAB80058.1 .
RefSeqi NP_561268.1. NC_003366.1.
WP_011009760.1. NC_003366.1.

3D structure databases

ProteinModelPortali Q8XNI1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 195102.CPE0352.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB80058 ; BAB80058 ; BAB80058 .
GeneIDi 988605.
KEGGi cpe:CPE0352.
PATRICi 19494610. VBICloPer59675_0410.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279960.
KOi K03703.
OMAi HRFVITF.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci CPER195102:GJFM-389-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 13 / Type A.

Entry informationi

Entry nameiUVRC_CLOPE
AccessioniPrimary (citable) accession number: Q8XNI1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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