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Protein

Glutaminase 1

Gene

glsA1

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei62SubstrateUniRule annotation1
Binding sitei114SubstrateUniRule annotation1
Binding sitei159SubstrateUniRule annotation1
Binding sitei166SubstrateUniRule annotation1
Binding sitei190SubstrateUniRule annotation1
Binding sitei242SubstrateUniRule annotation1
Binding sitei260Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase 1UniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsA1UniRule annotation
Ordered Locus Names:CPE0591
OrganismiClostridium perfringens (strain 13 / Type A)
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000818 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001106021 – 307Glutaminase 1Add BLAST307

Proteomic databases

PRIDEiQ8XMU7.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8XMU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000216890.
KOiK01425.
OMAiKIMNDDE.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8XMU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDINLDALVE ANRRYTKEGH VATYIPALAK VNPDQLGVCI YDLKENKEFS
60 70 80 90 100
AGEYDVRFAI ESISKVPTLI LAILDNGIEK VFSEVGTEPS GFAFNSIMNM
110 120 130 140 150
QINHKNKPSN PFINAGAIKV VSLLKGKNDE ERFKRILDFY RKIMNDDEIT
160 170 180 190 200
LDTEIYLSER ETGDINRSLA YYMKGNGIME GDVTDILDSY FKQCSVLVTA
210 220 230 240 250
KDLARLGAVL ANEGVMPWNG ERLFSVETAT VVKSLMTTYG LYDESGAFSV
260 270 280 290 300
HIGLPSKSGV GGGILSSVPN KCGIGLFSPA LDVSGNSVAS MKLLKEIADK

LKLDIFR
Length:307
Mass (Da):33,731
Last modified:March 1, 2002 - v1
Checksum:iBD3FCB7D09D975C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA. Translation: BAB80297.1.
RefSeqiWP_011009915.1. NC_003366.1.

Genome annotation databases

EnsemblBacteriaiBAB80297; BAB80297; BAB80297.
KEGGicpe:CPE0591.
PATRICi19495096. VBICloPer59675_0652.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA. Translation: BAB80297.1.
RefSeqiWP_011009915.1. NC_003366.1.

3D structure databases

ProteinModelPortaliQ8XMU7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ8XMU7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB80297; BAB80297; BAB80297.
KEGGicpe:CPE0591.
PATRICi19495096. VBICloPer59675_0652.

Phylogenomic databases

HOGENOMiHOG000216890.
KOiK01425.
OMAiKIMNDDE.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA1_CLOPE
AccessioniPrimary (citable) accession number: Q8XMU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2002
Last modified: November 30, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.