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Q8XMP3

- SYQ_CLOPE

UniProt

Q8XMP3 - SYQ_CLOPE

Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei269 – 2691ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glutamine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutaminyl-tRNA aminoacylation Source: InterPro
    2. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCPER195102:GJFM-687-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
    Alternative name(s):
    Glutaminyl-tRNA synthetaseUniRule annotation
    Short name:
    GlnRSUniRule annotation
    Gene namesi
    Name:glnSUniRule annotation
    Synonyms:gltX
    Ordered Locus Names:CPE0645
    OrganismiClostridium perfringens (strain 13 / Type A)
    Taxonomic identifieri195102 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000818: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 552552Glutamine--tRNA ligasePRO_0000195831Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi195102.CPE0645.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8XMP3.
    SMRiQ8XMP3. Positions 8-548.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi33 – 4311"HIGH" regionAdd
    BLAST
    Motifi266 – 2705"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0008.
    HOGENOMiHOG000259232.
    KOiK01886.
    OMAiSTVDIAM.
    OrthoDBiEOG6DRPF7.

    Family and domain databases

    Gene3Di1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    HAMAPiMF_00126. Gln_tRNA_synth.
    InterProiIPR001412. aa-tRNA-synth_I_CS.
    IPR004514. Gln-tRNA-synth.
    IPR022861. Gln_tRNA_ligase_bac.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR10119. PTHR10119. 1 hit.
    PfamiPF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    [Graphical view]
    PRINTSiPR00987. TRNASYNTHGLU.
    SUPFAMiSSF50715. SSF50715. 1 hit.
    TIGRFAMsiTIGR00440. glnS. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8XMP3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNAEHSSNF IRNIIIDDLD SKKHDTIITR FPPEPNGYLH IGHAKSIVLN    50
    FELGKEFNGR TNLRFDDTNP TKEDTEYVES IKEDVHWLGY NWSELHFASN 100
    YFDEMYKRAL LLIKKGKAYV CDLTPEEIKE YRGTLTEPGK ESPYRNRSIE 150
    ENLDLFERMR KGEFEDGSKV LRAKIDMSSP NINFRDPIIY RIAHASHHNT 200
    GDKWCIYPMY DFAHPLEDAI EGITHSICTL EFADHRPLYD WFVKECEMES 250
    VPRQIEFARL NITNTVMSKR KLKQLVDEGI VDGWDDPRMP TVAGLRRRGY 300
    TPKSIRNFCK AIGVAKADST VDSQMLEHFI REDLQETAPR AMAVINPLKL 350
    VITNYPEGES EILEIENNPK DESAGKRAVT FSREVYIERE DFMENPPKKY 400
    FRLFPGNEVR LKGAYFVKCN EVIKDENGEV TEIHCTYDPE TKSGTGFTGR 450
    KVKGTIHWVD ANNCIPAEFR LYEPLILDDC EENEGKHFLE QINPNSLTIC 500
    KGFIEPSAKD AKPQDKYQLF RHGYFNVDPN FTSDDNLVFN RIVSLKSSFK 550
    LK 552
    Length:552
    Mass (Da):63,933
    Last modified:March 1, 2002 - v1
    Checksum:iA349EA7211F66F1D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000016 Genomic DNA. Translation: BAB80351.1.
    RefSeqiNP_561561.1. NC_003366.1.

    Genome annotation databases

    EnsemblBacteriaiBAB80351; BAB80351; BAB80351.
    GeneIDi988903.
    KEGGicpe:CPE0645.
    PATRICi19495214. VBICloPer59675_0707.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000016 Genomic DNA. Translation: BAB80351.1 .
    RefSeqi NP_561561.1. NC_003366.1.

    3D structure databases

    ProteinModelPortali Q8XMP3.
    SMRi Q8XMP3. Positions 8-548.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 195102.CPE0645.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB80351 ; BAB80351 ; BAB80351 .
    GeneIDi 988903.
    KEGGi cpe:CPE0645.
    PATRICi 19495214. VBICloPer59675_0707.

    Phylogenomic databases

    eggNOGi COG0008.
    HOGENOMi HOG000259232.
    KOi K01886.
    OMAi STVDIAM.
    OrthoDBi EOG6DRPF7.

    Enzyme and pathway databases

    BioCyci CPER195102:GJFM-687-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    HAMAPi MF_00126. Gln_tRNA_synth.
    InterProi IPR001412. aa-tRNA-synth_I_CS.
    IPR004514. Gln-tRNA-synth.
    IPR022861. Gln_tRNA_ligase_bac.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR10119. PTHR10119. 1 hit.
    Pfami PF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00987. TRNASYNTHGLU.
    SUPFAMi SSF50715. SSF50715. 1 hit.
    TIGRFAMsi TIGR00440. glnS. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 13 / Type A.

    Entry informationi

    Entry nameiSYQ_CLOPE
    AccessioniPrimary (citable) accession number: Q8XMP3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 2, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3