Q8XLB0 (Q8XLB0_CLOPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Lysozyme RuleBase RU003788
EC=3.2.1.17 RuleBase RU003788

Gene names

Ordered Locus Names:

CPE1132

Organism

Clostridium perfringens [Complete proteome] [HAMAP]

Taxonomic identifier

1502 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	983 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. RuleBase RU003788
Sequence similarities	Belongs to the glycosyl hydrolase 24 family. RuleBase RU003788

Ontologies

Keywords
Molecular function	Antimicrobial Bacteriolytic enzyme RuleBase RU003788 Glycosidase RuleBase RU003788 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8XLB0 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: E6044FFEB3D15164	FASTA	983	110,428
	10 20 30 40 50 60 MQYYKIDNYN FVKNGDITLQ PIDGKLRLEL NTGLNEIEFE LGYDKEKRWT RIEEWGVIKT 70 80 90 100 110 120 DVFYSKNKQL YRIYNIDKGM FSLKIKARHI FFDLVKHNLL DTRAVACNGQ QALERILEGT 130 140 150 160 170 180 KYKGHSDIDR INTCYFCVTN IVQAINGEND NSFRNRWGGE MLFDNFDIYI NNRIGGDYGV 190 200 210 220 230 240 RVNYSRNMED VNLIIDRDNI VTRAYPRAFD GIMLPEKYID SPLINKYPIV CEDYIDMSDL 250 260 270 280 290 300 KLKDPNTSND EGFDTEEELY QAMRERMKKL YEGGIDKPSI SGNVKVAMLE NSIEYKDFKG 310 320 330 340 350 360 LVNIGIGDTV TVNHKDIDID MKTRAITIEW NLVTKKYENI EFGDVEVNYF AKQDIAREQL 370 380 390 400 410 420 DNILNKNGTV NAGEMEGIIN AMQTKFKALR DVAQPQHTLG MLFEDKIKGS ATYGAMAIGS 430 440 450 460 470 480 MGFMIASERT EDDKDWNWKT FGSGQGFFAD WLVGKLRTVL IENMDGSFQM DLNKPGGMIF 490 500 510 520 530 540 KNNGLKSMLI ENNALKMFNW KKDEQYIGGL TSLIAGDNKE KPLVGLTNSP KAAINIGYEK 550 560 570 580 590 600 KEDTKVVPSY VQFDKYNVLG DEDGKPIRIW EDIDAKGSSV YNINLKSKDD KSWITVKDGE 610 620 630 640 650 660 LSLKYKDQFL MITDKGITLK GDVILDGVIK NTSGNLVLDP NAPQGGGVDG SDSLRNSVVN 670 680 690 700 710 720 SARKLIGKPY VWGGNYPPLG SDVGTDCSGL MQWSYHDNGI TLSRTTYTQI NEGFEVKENE 730 740 750 760 770 780 LKPGDLIFMH FTAPNTPQHV FMYSGEKDGQ HMCVEAPRTG LNIRERAFTW GSDYRARRII 790 800 810 820 830 840 KDTPGGNVNG NAGTKASKNI IYYVKGIEGY APYHYYDSVG VKTLGYGMTG SELSGVSVPL 850 860 870 880 890 900 SETSATHYLV DNFNRLYYTP VLNMLKARGA TNMLQREVDA LASFAYNCGL DSNGLGGSQL 910 920 930 940 950 960 LKKYVAGERG ESIHNEFKKW VHGGGQVLPG LVRRREEEWK IFSGSSSPVG GYNTTPSISY 970 980 IGTNGLPTGR VVTENGGYGA SPY

References

[1]

"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater." Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H. Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed: 11792842] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000016 Genomic DNA. Translation: BAB80838.1.
RefSeq	NP_562048.1. NC_003366.1.
3D structure databases
ProteinModelPortal	Q8XLB0.
ModBase	Search...
Protein family/group databases
CAZy	GH24. Glycoside Hydrolase Family 24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	989441.
GenomeReviews	Gene locus CPE1132 in contig BA000016_GR.
KEGG	cpe:CPE1132.
NMPDR	fig|195102.1.peg.1195.
PATRIC	19496210. VBICloPer59675_1202.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MIASERT.
PhylomeDB	Q8XLB0.
ProtClustDB	CLSK518967.
Family and domain databases
InterPro	IPR002196. Glyco_hydro_24. IPR023346. Lysozyme-like_dom. IPR023347. Lysozyme_dom. IPR000064. NLP_P60. IPR010572. Phage_53_Orf003. IPR007119. Phage_minor_struct_N. [Graphical view]
Gene3D	G3DSA:1.10.530.40. G3DSA:1.10.530.40. 1 hit.
Pfam	PF00877. NLPC_P60. 1 hit. PF00959. Phage_lysozyme. 1 hit. PF06605. Prophage_tail. 1 hit. [Graphical view]
SUPFAM	SSF53955. SSF53955. 1 hit.
TIGRFAMs	TIGR01665. Put_anti_recept. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8XLB0_CLOPE

Accession

Primary (citable) accession number: Q8XLB0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)