Reviewed, UniProtKB/Swiss-Prot Q8XKP8 (GALT_CLOPE)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	CPE1346

Organism

Clostridium perfringens [Complete proteome] [HAMAP]

Taxonomic identifier

1502 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 498	498	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169903

Sequences

	Sequence		Length	Mass (Da)
	Q8XKP8-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: C99AD9BC69C78E11	FASTA	498	57,928
	10 20 30 40 50 60 MYNLNALIDR LIEISINNNL IEDMDTVYTR NRLLSLFNEN SYTPCEEKLT LSFHETLNEL 70 80 90 100 110 120 INIAIEKKII ENALYSKDIF SSDIMNIFLP TPSLINKEFY KRYAISPKES TDYFYSLSKS 130 140 150 160 170 180 SNYIRTDRIA KNINFKAPSK YGTMDITINL SKPEKDPKEI ALARNSVKSN YPKCLLCIEN 190 200 210 220 230 240 EGYEGTVTHP DRANHRMIRL DLNDRTWMLQ YSPYLYYNEH CIILSEDHVP MKIDISTFKN 250 260 270 280 290 300 LLSFVDKFPH YFTGSNADLP IVGGSILSHE HYQGGNHRFP MNDAKKLFDF SIEGFEDVEC 310 320 330 340 350 360 EAIKWPISTI RLRGENIDSL VLASDLILKK WRDYSDETLD ILAYSNSEMH NTITPMVRKE 370 380 390 400 410 420 DGKFVVDLSL RNNRTSKEHP LGIFHPHEEV HHIKKENIGL IEVMGLAVLP GRLLKELEKI 430 440 450 460 470 480 KEYLRDEISL DNIEEYHRPW ALELKKKFDY LKSSTDLNDF VNKELSNKFV SVLEHCGVFK 490 LNEEGLEGFK RFTNSLNS

References

[1]

"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater." Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H. Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed: 11792842] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13 / Type A.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000016 Genomic DNA. Translation: BAB81052.1.
RefSeq	NP_562262.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	989655.
GenomeReviews	Gene locus CPE1346 in contig BA000016_GR.
KEGG	cpe:CPE1346.
NMPDR	fig|195102.1.peg.1409.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8XKP8.
OMA	EHYQGGR.
Enzyme and pathway databases
BioCyc	CPER195102:CPE1346-MON.
BRENDA	2.7.7.12. 2406.
Family and domain databases
HAMAP	MF_00571. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_CLOPE

Accession

Primary (citable) accession number: Q8XKP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)