Reviewed, UniProtKB/Swiss-Prot Q8XJZ6 (MSRB_CLOPE)

Names and origin

Protein names

Recommended name:
    Peptide methionine sulfoxide reductase msrB
    EC=1.8.4.12
Alternative name(s):
    Peptide-methionine (R)-S-oxide reductase

Gene names

Name:	msrB
Ordered Locus Names:	CPE1607

Organism

Clostridium perfringens [Complete proteome] [HAMAP]

Taxonomic identifier

1502 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Sequence similarities	Belongs to the msrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 147	147	Peptide methionine sulfoxide reductase msrB HAMAP MF_01400		PRO_0000140269
Sites
	Active site	120	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8XJZ6-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: B2290C2ACCD4654B	FASTA	147	17,118
	10 20 30 40 50 60 MKYTKKEKEE LKKVLTEEEY YVTQENGTER PFTNEYWDFN GEGIYVDITT GEPLFTSKDK 70 80 90 100 110 120 FHSSCGWPAF SKPIDRSIIK EKVDKSHGMI RTEVRSKLGD SHLGHVFCDG PEELGGLRYC 130 140 INSASLKFIP KEELKEKGYE EYLELFK

References

[1]

"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater." Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H. Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed: 11792842] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000016 Genomic DNA. Translation: BAB81313.1.
RefSeq	NP_562523.1.
3D structure databases
SMR	Q8XJZ6. Positions 8-146.
ModBase	Search...
Genome annotation databases
GeneID	989917.
GenomeReviews	Gene locus CPE1607 in contig BA000016_GR.
KEGG	cpe:CPE1607.
NMPDR	fig|195102.1.peg.1670.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG715255.
OMA	DKYESGC.
Enzyme and pathway databases
BioCyc	CPER195102:CPE1607-MONOMER.
BRENDA	1.8.4.12. 2406.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00357. MsrB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_CLOPE

Accession

Primary (citable) accession number: Q8XJZ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 2002
Last sequence update:	March 1, 2002
Last modified:	February 9, 2010
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)