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Q8XJL8 (PKN2_CLOPE) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable serine/threonine-protein kinase CPE1738

EC=2.7.11.1
Gene names
Ordered Locus Names:CPE1738
OrganismClostridium perfringens (strain 13 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier195102 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length685 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 4 PASTA domains.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 685685Probable serine/threonine-protein kinase CPE1738
PRO_0000171195

Regions

Domain10 – 275266Protein kinase
Domain376 – 44065PASTA 1
Domain441 – 50868PASTA 2
Domain513 – 58169PASTA 3
Domain589 – 64860PASTA 4
Nucleotide binding16 – 249ATP By similarity

Sites

Active site1431Proton acceptor By similarity
Binding site391ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8XJL8 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 75A396084485EB24

FASTA68574,576
        10         20         30         40         50         60 
MIGKILGNRY ELLQCVGEGG MSFVYKARCR KLNRFVAVKI LKDEFKNNEE IVRRFKKEAT 

        70         80         90        100        110        120 
AIANLSNPNV VNVLDVGTQD DINYIVMEYV EGKTLKDIIK EKGALPYEVA ISIGIKVAKA 

       130        140        150        160        170        180 
LECAHKSGII HRDVKPQNIL VTEEGVVKVT DFGIAKSMDS STIAHTNSVM GSAHYFSPEQ 

       190        200        210        220        230        240 
AKGTYTDYRT DLYSLGIVLY EMVTGVVPFN GDSPVTVAVK HIQEKAIPPK NINQNIPNSL 

       250        260        270        280        290        300 
NDLIMKAMEK DPVNRYQTAK EIIGDLEKIK KDPNVTISSK SAEDEDQFTR VMSPVVVPNT 

       310        320        330        340        350        360 
ETNNSEPDED DEDDDEYYED DEDEDEEENN IQTKPQKAIN KNKKKSPILI IIATILVVAL 

       370        380        390        400        410        420 
GITLGFLGMK KFMEGGKDVK IPNVVGEKVE DAKSKLEGLG LKVLEVTEES DQEKGIVLKV 

       430        440        450        460        470        480 
DPNVDSTVKT GSEVKLTVSG GEGQIKVPNF AEMNLDSVKR TLKSLGLELG SVDEEYSDSV 

       490        500        510        520        530        540 
PRGEVISQSP NANESVDKGS KVNVTISKGK EIKSETINIP DVSGKSVEEA KSILANAGVG 

       550        560        570        580        590        600 
VNPVKGEAAK SEGEAGKVYS QSQSGSLTIK QGEKVTITIN YYGDYVKPEK PKHNAGELVG 

       610        620        630        640        650        660 
MTGAQAKAWA SKNKINVSGI TSDTAKVKSV SNSGEVEEGG SVSVTMEEEK KPEQPTQPNQ 

       670        680 
PTQPTQPNQQ AQPEQPKQPE QSGNN 

« Hide

References

[1]"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater."
Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H.
Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 13 / Type A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000016 Genomic DNA. Translation: BAB81444.1.
RefSeqNP_562654.1. NC_003366.1.

3D structure databases

ProteinModelPortalQ8XJL8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING195102.CPE1738.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB81444; BAB81444; BAB81444.
GeneID990048.
KEGGcpe:CPE1738.
PATRIC19497431. VBICloPer59675_1811.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000037185.
KOK08884.
OMATGKDPGT.
OrthoDBEOG6B35XT.
ProtClustDBCLSK811119.

Enzyme and pathway databases

BioCycCPER195102:GJFM-1785-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR005543. PASTA.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN2_CLOPE
AccessionPrimary (citable) accession number: Q8XJL8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2002
Last modified: November 13, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families