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Q8XJL8

- PKN2_CLOPE

UniProt

Q8XJL8 - PKN2_CLOPE

Protein

Probable serine/threonine-protein kinase CPE1738

Gene

CPE1738

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391ATPPROSITE-ProRule annotation
    Active sitei143 – 1431Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi16 – 249ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. penicillin binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCPER195102:GJFM-1785-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase CPE1738 (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:CPE1738
    OrganismiClostridium perfringens (strain 13 / Type A)
    Taxonomic identifieri195102 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000818: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 685685Probable serine/threonine-protein kinase CPE1738PRO_0000171195Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi195102.CPE1738.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8XJL8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 275266Protein kinasePROSITE-ProRule annotationAdd
    BLAST
    Domaini376 – 44065PASTA 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini441 – 50868PASTA 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini513 – 58169PASTA 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini589 – 64860PASTA 4PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 4 PASTA domains.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000037185.
    KOiK08884.
    OMAiKVLRPEY.
    OrthoDBiEOG6B35XT.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 4 hits.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 4 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8XJL8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIGKILGNRY ELLQCVGEGG MSFVYKARCR KLNRFVAVKI LKDEFKNNEE    50
    IVRRFKKEAT AIANLSNPNV VNVLDVGTQD DINYIVMEYV EGKTLKDIIK 100
    EKGALPYEVA ISIGIKVAKA LECAHKSGII HRDVKPQNIL VTEEGVVKVT 150
    DFGIAKSMDS STIAHTNSVM GSAHYFSPEQ AKGTYTDYRT DLYSLGIVLY 200
    EMVTGVVPFN GDSPVTVAVK HIQEKAIPPK NINQNIPNSL NDLIMKAMEK 250
    DPVNRYQTAK EIIGDLEKIK KDPNVTISSK SAEDEDQFTR VMSPVVVPNT 300
    ETNNSEPDED DEDDDEYYED DEDEDEEENN IQTKPQKAIN KNKKKSPILI 350
    IIATILVVAL GITLGFLGMK KFMEGGKDVK IPNVVGEKVE DAKSKLEGLG 400
    LKVLEVTEES DQEKGIVLKV DPNVDSTVKT GSEVKLTVSG GEGQIKVPNF 450
    AEMNLDSVKR TLKSLGLELG SVDEEYSDSV PRGEVISQSP NANESVDKGS 500
    KVNVTISKGK EIKSETINIP DVSGKSVEEA KSILANAGVG VNPVKGEAAK 550
    SEGEAGKVYS QSQSGSLTIK QGEKVTITIN YYGDYVKPEK PKHNAGELVG 600
    MTGAQAKAWA SKNKINVSGI TSDTAKVKSV SNSGEVEEGG SVSVTMEEEK 650
    KPEQPTQPNQ PTQPTQPNQQ AQPEQPKQPE QSGNN 685
    Length:685
    Mass (Da):74,576
    Last modified:March 1, 2002 - v1
    Checksum:i75A396084485EB24
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000016 Genomic DNA. Translation: BAB81444.1.
    RefSeqiNP_562654.1. NC_003366.1.

    Genome annotation databases

    EnsemblBacteriaiBAB81444; BAB81444; BAB81444.
    GeneIDi990048.
    KEGGicpe:CPE1738.
    PATRICi19497431. VBICloPer59675_1811.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000016 Genomic DNA. Translation: BAB81444.1 .
    RefSeqi NP_562654.1. NC_003366.1.

    3D structure databases

    ProteinModelPortali Q8XJL8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 195102.CPE1738.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB81444 ; BAB81444 ; BAB81444 .
    GeneIDi 990048.
    KEGGi cpe:CPE1738.
    PATRICi 19497431. VBICloPer59675_1811.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000037185.
    KOi K08884.
    OMAi KVLRPEY.
    OrthoDBi EOG6B35XT.

    Enzyme and pathway databases

    BioCyci CPER195102:GJFM-1785-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 3 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 4 hits.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 4 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 13 / Type A.

    Entry informationi

    Entry nameiPKN2_CLOPE
    AccessioniPrimary (citable) accession number: Q8XJL8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3