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Q8XJL8

- PKN2_CLOPE

UniProt

Q8XJL8 - PKN2_CLOPE

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Protein

Probable serine/threonine-protein kinase CPE1738

Gene

CPE1738

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATPPROSITE-ProRule annotation
Active sitei143 – 1431Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPER195102:GJFM-1785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase CPE1738 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:CPE1738
OrganismiClostridium perfringens (strain 13 / Type A)
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000818: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 685685Probable serine/threonine-protein kinase CPE1738PRO_0000171195Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi195102.CPE1738.

Structurei

3D structure databases

ProteinModelPortaliQ8XJL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 275266Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini376 – 44065PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini441 – 50868PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini513 – 58169PASTA 3PROSITE-ProRule annotationAdd
BLAST
Domaini589 – 64860PASTA 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 4 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiKVLRPEY.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8XJL8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIGKILGNRY ELLQCVGEGG MSFVYKARCR KLNRFVAVKI LKDEFKNNEE
60 70 80 90 100
IVRRFKKEAT AIANLSNPNV VNVLDVGTQD DINYIVMEYV EGKTLKDIIK
110 120 130 140 150
EKGALPYEVA ISIGIKVAKA LECAHKSGII HRDVKPQNIL VTEEGVVKVT
160 170 180 190 200
DFGIAKSMDS STIAHTNSVM GSAHYFSPEQ AKGTYTDYRT DLYSLGIVLY
210 220 230 240 250
EMVTGVVPFN GDSPVTVAVK HIQEKAIPPK NINQNIPNSL NDLIMKAMEK
260 270 280 290 300
DPVNRYQTAK EIIGDLEKIK KDPNVTISSK SAEDEDQFTR VMSPVVVPNT
310 320 330 340 350
ETNNSEPDED DEDDDEYYED DEDEDEEENN IQTKPQKAIN KNKKKSPILI
360 370 380 390 400
IIATILVVAL GITLGFLGMK KFMEGGKDVK IPNVVGEKVE DAKSKLEGLG
410 420 430 440 450
LKVLEVTEES DQEKGIVLKV DPNVDSTVKT GSEVKLTVSG GEGQIKVPNF
460 470 480 490 500
AEMNLDSVKR TLKSLGLELG SVDEEYSDSV PRGEVISQSP NANESVDKGS
510 520 530 540 550
KVNVTISKGK EIKSETINIP DVSGKSVEEA KSILANAGVG VNPVKGEAAK
560 570 580 590 600
SEGEAGKVYS QSQSGSLTIK QGEKVTITIN YYGDYVKPEK PKHNAGELVG
610 620 630 640 650
MTGAQAKAWA SKNKINVSGI TSDTAKVKSV SNSGEVEEGG SVSVTMEEEK
660 670 680
KPEQPTQPNQ PTQPTQPNQQ AQPEQPKQPE QSGNN
Length:685
Mass (Da):74,576
Last modified:March 1, 2002 - v1
Checksum:i75A396084485EB24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA. Translation: BAB81444.1.
RefSeqiNP_562654.1. NC_003366.1.
WP_004458146.1. NC_003366.1.

Genome annotation databases

EnsemblBacteriaiBAB81444; BAB81444; BAB81444.
GeneIDi990048.
KEGGicpe:CPE1738.
PATRICi19497431. VBICloPer59675_1811.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA. Translation: BAB81444.1 .
RefSeqi NP_562654.1. NC_003366.1.
WP_004458146.1. NC_003366.1.

3D structure databases

ProteinModelPortali Q8XJL8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 195102.CPE1738.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB81444 ; BAB81444 ; BAB81444 .
GeneIDi 990048.
KEGGi cpe:CPE1738.
PATRICi 19497431. VBICloPer59675_1811.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi KVLRPEY.
OrthoDBi EOG6B35XT.

Enzyme and pathway databases

BioCyci CPER195102:GJFM-1785-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 4 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 13 / Type A.

Entry informationi

Entry nameiPKN2_CLOPE
AccessioniPrimary (citable) accession number: Q8XJL8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2002
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3