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Q8XJL8

- PKN2_CLOPE

UniProt

Q8XJL8 - PKN2_CLOPE

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Protein

Probable serine/threonine-protein kinase CPE1738

Gene
CPE1738
Organism
Clostridium perfringens (strain 13 / Type A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391ATP By similarity
Active sitei143 – 1431Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi16 – 249ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPER195102:GJFM-1785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase CPE1738 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:CPE1738
OrganismiClostridium perfringens (strain 13 / Type A)
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000818: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 685685Probable serine/threonine-protein kinase CPE1738PRO_0000171195Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi195102.CPE1738.

Structurei

3D structure databases

ProteinModelPortaliQ8XJL8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 275266Protein kinaseAdd
BLAST
Domaini376 – 44065PASTA 1Add
BLAST
Domaini441 – 50868PASTA 2Add
BLAST
Domaini513 – 58169PASTA 3Add
BLAST
Domaini589 – 64860PASTA 4Add
BLAST

Sequence similaritiesi

Contains 4 PASTA domains.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
KOiK08884.
OMAiKVLRPEY.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8XJL8-1 [UniParc]FASTAAdd to Basket

« Hide

MIGKILGNRY ELLQCVGEGG MSFVYKARCR KLNRFVAVKI LKDEFKNNEE    50
IVRRFKKEAT AIANLSNPNV VNVLDVGTQD DINYIVMEYV EGKTLKDIIK 100
EKGALPYEVA ISIGIKVAKA LECAHKSGII HRDVKPQNIL VTEEGVVKVT 150
DFGIAKSMDS STIAHTNSVM GSAHYFSPEQ AKGTYTDYRT DLYSLGIVLY 200
EMVTGVVPFN GDSPVTVAVK HIQEKAIPPK NINQNIPNSL NDLIMKAMEK 250
DPVNRYQTAK EIIGDLEKIK KDPNVTISSK SAEDEDQFTR VMSPVVVPNT 300
ETNNSEPDED DEDDDEYYED DEDEDEEENN IQTKPQKAIN KNKKKSPILI 350
IIATILVVAL GITLGFLGMK KFMEGGKDVK IPNVVGEKVE DAKSKLEGLG 400
LKVLEVTEES DQEKGIVLKV DPNVDSTVKT GSEVKLTVSG GEGQIKVPNF 450
AEMNLDSVKR TLKSLGLELG SVDEEYSDSV PRGEVISQSP NANESVDKGS 500
KVNVTISKGK EIKSETINIP DVSGKSVEEA KSILANAGVG VNPVKGEAAK 550
SEGEAGKVYS QSQSGSLTIK QGEKVTITIN YYGDYVKPEK PKHNAGELVG 600
MTGAQAKAWA SKNKINVSGI TSDTAKVKSV SNSGEVEEGG SVSVTMEEEK 650
KPEQPTQPNQ PTQPTQPNQQ AQPEQPKQPE QSGNN 685
Length:685
Mass (Da):74,576
Last modified:March 1, 2002 - v1
Checksum:i75A396084485EB24
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000016 Genomic DNA. Translation: BAB81444.1.
RefSeqiNP_562654.1. NC_003366.1.

Genome annotation databases

EnsemblBacteriaiBAB81444; BAB81444; BAB81444.
GeneIDi990048.
KEGGicpe:CPE1738.
PATRICi19497431. VBICloPer59675_1811.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000016 Genomic DNA. Translation: BAB81444.1 .
RefSeqi NP_562654.1. NC_003366.1.

3D structure databases

ProteinModelPortali Q8XJL8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 195102.CPE1738.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB81444 ; BAB81444 ; BAB81444 .
GeneIDi 990048.
KEGGi cpe:CPE1738.
PATRICi 19497431. VBICloPer59675_1811.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
KOi K08884.
OMAi KVLRPEY.
OrthoDBi EOG6B35XT.

Enzyme and pathway databases

BioCyci CPER195102:GJFM-1785-MONOMER.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 4 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 13 / Type A.

Entry informationi

Entry nameiPKN2_CLOPE
AccessioniPrimary (citable) accession number: Q8XJL8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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