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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
OrganismiClostridium perfringens (strain 13 / Type A)Imported
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000818 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ8XJJ1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 324Tubulin_CInterPro annotationAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili342 – 362Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XJJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDFDVDIQS FTNIKVIGCG GGGGNAVNRM IQEGLRDVEF IAINTDKQAL
60 70 80 90 100
TLSHAQNKIQ IGDKLTKGLG AGANPEIGKK AAEESRDEIT EAISGADMVF
110 120 130 140 150
ITAGMGGGTG TGAAPVVAEI AKSMGILTVG IVTKPFPFEG RRRMTHAEMG
160 170 180 190 200
IANLKEKVDT LVTIPNERLL SMVDKKTTLL ESFKKADDVL RQGVQGISDL
210 220 230 240 250
ITNPGLINLD FADVRAVMLD KGLAHMGVGY GKGETRAQDA AREAISSPLL
260 270 280 290 300
ETSIVGATGV LLNVTGDSEL GLLEINEAAE IVQEAADPDA NIIFGTVIDE
310 320 330 340 350
TLKDEIRITV IATGFEKERQ RMGMGAQGVT SGATQTQREV IVENVEEKVA
360 370 380
EQEVAASSQT QQEDRYNDDL EIPMFLRRGR R
Length:381
Mass (Da):40,713
Last modified:March 1, 2002 - v1
Checksum:i143F12617FC49AE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA Translation: BAB81471.1
RefSeqiWP_003449411.1, NC_003366.1

Genome annotation databases

EnsemblBacteriaiBAB81471; BAB81471; BAB81471
GeneIDi29570879
KEGGicpe:CPE1765

Similar proteinsi

Entry informationi

Entry nameiQ8XJJ1_CLOPE
AccessioniPrimary (citable) accession number: Q8XJJ1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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