Reviewed, UniProtKB/Swiss-Prot Q8XIZ0 (ACYP_CLOPE)

Names and origin

Protein names

Recommended name:
    Acylphosphatase
    EC=3.6.1.7
Alternative name(s):
    Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	CPE1973

Organism

Clostridium perfringens [Complete proteome] [HAMAP]

Taxonomic identifier

1502 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	89 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 89	89	Acylphosphatase HAMAP MF_01450		PRO_0000326685
Regions
	Domain	3 – 89	87	Acylphosphatase-like
Sites
	Active site	18	1	By similarity
	Active site	36	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8XIZ0-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 4A1456CC90D093E5	FASTA	89	10,162
	10 20 30 40 50 60 MIRKEFLVSG RVQGVGFRFF CKYQASLLSL TGYAENLDDG QVLIEVQGDE SSIRKFKTKI 70 80 LNGNGFSRVI SIDEKDLTVD TREKRFSTY

References

[1]

"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater." Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H. Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed: 11792842] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000016 Genomic DNA. Translation: BAB81679.1.
RefSeq	NP_562889.1.
3D structure databases
HSSP	HSSP built from PDB template 2BJD based on UniProtKB Q97ZL0.
SMR	Q8XIZ0. Positions 1-89.
ModBase	Search...
Genome annotation databases
GeneID	990287.
GenomeReviews	Gene locus CPE1973 in contig BA000016_GR.
KEGG	cpe:CPE1973.
NMPDR	fig|195102.1.peg.2036.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG750266.
OMA	PFSKVTD.
PhylomeDB	Q8XIZ0.
Enzyme and pathway databases
BioCyc	CPER195102:CPE1973-MONOMER.
BRENDA	3.6.1.7. 2406.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
PANTHER	PTHR10029. Acylphosphatase. 1 hit.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_CLOPE

Accession

Primary (citable) accession number: Q8XIZ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	March 1, 2002
Last modified:	January 19, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)