Reviewed, UniProtKB/Swiss-Prot Q8XIR2 (DEOC_CLOPE)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	CPE2052

Organism

Clostridium perfringens [Complete proteome] [HAMAP]

Taxonomic identifier

1502 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	224 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 224	224	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_0000057227
Sites
	Active site	155	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	184	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8XIR2-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 125F5CCDA81212BD	FASTA	224	23,926
	10 20 30 40 50 60 MDKQQLAKMI DHTILKPEAD KASIEKLCKE ALEYNFASVC INPTNVELAA KLLKGSEVKV 70 80 90 100 110 120 CTVIGFPLGA NTMEVKAFET KDAIAKGADE VDMVINIGRL KDKDYEYVEK DIKAVVDAAD 130 140 150 160 170 180 KKALTKVIIE TCLLTEEEKV KACELAKKAG ADFVKTSTGF STGGATPEDI KLMRETVGPE 190 200 210 220 MGVKASGGVR SIEDAEAVIK NGATRIGASA SIAICEGKVS DSTY

References

[1]

"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater." Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H. Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed: 11792842] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13 / Type A.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000016 Genomic DNA. Translation: BAB81758.1.
RefSeq	NP_562968.1.
3D structure databases
HSSP	HSSP built from PDB template 1O0Y based on UniProtKB Q9X1P5.
ModBase	Search...
Genome annotation databases
GeneID	990367.
GenomeReviews	Gene locus CPE2052 in contig BA000016_GR.
KEGG	cpe:CPE2052.
NMPDR	fig|195102.1.peg.2115.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8XIR2.
OMA	AKMIDHT.
Enzyme and pathway databases
BioCyc	CPER195102:CPE2052-MON.
BRENDA	4.1.2.4. 2406.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_CLOPE

Accession

Primary (citable) accession number: Q8XIR2

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 2, 2002
Last sequence update:	March 1, 2002
Last modified:	November 3, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)