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Protein

Glutamate decarboxylase

Gene

CPE2058

Organism
Clostridium perfringens (strain 13 / Type A)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciCPER195102:GJFM-2109-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:CPE2058Imported
OrganismiClostridium perfringens (strain 13 / Type A)Imported
Taxonomic identifieri195102 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000818 Componenti: Chromosome

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1075168

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei276N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliQ8XIQ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XIQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFGKNELGS QFETPIFGTV ESNESIPKYE LAKKSIAPQV AYRLIKDDLL
60 70 80 90 100
DEGNARQNLC TFCQTYMDDE AVKLMAETLE KNAIDKSEYP QTTDLENRCV
110 120 130 140 150
NILADLWHAP KDESFMGTST VGSSEACMLG GMAMKFRWRN RAKALGMDVT
160 170 180 190 200
SRKPNLVISS GYQVCWEKFC VYWDIEMRLV PMDEEHMSIN VDKVLDYVDD
210 220 230 240 250
YTIGVVGILG ITYTGKYDDI KALDKKLEEY NKTAKLTVPM HIDAASGGMF
260 270 280 290 300
APFIEPELEW DFRLKNVVSI STSGHKYGLV YPGIGWVLWR DKEYLPQELV
310 320 330 340 350
FDVSYLGGKI PTMAINFSRS ASQIIGQYYN FLRYGFEGYR QIHQRTKDVA
360 370 380 390 400
MFLASELEKT GLFQIYNNGE NLPIVCYKLR DDVNVDWTLY DLADRLLMKG
410 420 430 440 450
WQVPAYPLPA DLQDTIIQRI VCRADLSHNL AELYLRDLKA AIEDLNNARV
460
LNQKSKTGVQ GFTH
Length:464
Mass (Da):52,940
Last modified:March 1, 2002 - v1
Checksum:i1B242027E4787DAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000016 Genomic DNA Translation: BAB81764.1
RefSeqiWP_003455061.1, NC_003366.1

Genome annotation databases

EnsemblBacteriaiBAB81764; BAB81764; BAB81764
GeneIDi29570578
KEGGicpe:CPE2058

Similar proteinsi

Entry informationi

Entry nameiQ8XIQ6_CLOPE
AccessioniPrimary (citable) accession number: Q8XIQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health