Q8XHC9 (COMB_CLOPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	CPE2556

Organism

Clostridium perfringens [Complete proteome] [HAMAP]

Taxonomic identifier

1502 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081466

Sequences

	Sequence		Length	Mass (Da)
	Q8XHC9 [UniParc]. Last modified March 27, 2002. Version 1. Checksum: 3820A2CF1B696082	FASTA	247	27,190
	10 20 30 40 50 60 MKIDVIISAD YIDSESLKGK IAVVIDMLRA TSVITTALYN GAKKVIPVVS VEEAFEKANE 70 80 90 100 110 120 LKSLGEEVLL GGERKALKID GFDFSNSPLE YKREIVEGKN VIMSTTNGTR ALNLCNKADK 130 140 150 160 170 180 VIVASVLNGQ AVAKYLENEE KEIVFVNSGT NGEFSSDDFM CAGYIISEIC KNKEAELTDI 190 200 210 220 230 240 AKTAKYVCES SEGIEEFIKD AKHYNILKNL GLEEDLKYCS TKNLIDLVFE FKNGEIKTVE SGVKVTI

References

[1]

"Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater." Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H. Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002) [PubMed: 11792842] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 13 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000016 Genomic DNA. Translation: BAB82262.1.
RefSeq	NP_563472.1. NC_003366.1.
3D structure databases
ProteinModelPortal	Q8XHC9.
SMR	Q8XHC9. Positions 1-236.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	990933.
GenomeReviews	Gene locus CPE2556 in contig BA000016_GR.
KEGG	cpe:CPE2556.
NMPDR	fig|195102.1.peg.2619.
PATRIC	19499205. VBICloPer59675_2627.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG633644.
OMA	VPCHREN.
PhylomeDB	Q8XHC9.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	CPER195102:CPE2556-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_CLOPE

Accession

Primary (citable) accession number: Q8XHC9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 27, 2002
Last sequence update:	March 27, 2002
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program