Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

D-serine dehydratase

Gene

dsdA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-serine = pyruvate + NH3.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandPyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
D-serine dehydrataseUniRule annotation (EC:4.3.1.18UniRule annotation)
Alternative name(s):
D-serine deaminaseUniRule annotation
Short name:
DSDUniRule annotation
Gene namesi
Name:dsdAUniRule annotation
Ordered Locus Names:Z3628, ECs3245
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001856131 – 442D-serine dehydrataseAdd BLAST442

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei118N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi155864.Z3628

Structurei

3D structure databases

ProteinModelPortaliQ8XCK5
SMRiQ8XCK5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serine/threonine dehydratase family. DsdA subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105BZC Bacteria
COG3048 LUCA
HOGENOMiHOG000218072
KOiK01753
OMAiESDPNCF

Family and domain databases

HAMAPiMF_01030 D_Ser_dehydrat, 1 hit
InterProiView protein in InterPro
IPR011780 D_Ser_am_lyase
IPR001926 PLP-dep
IPR000634 Ser/Thr_deHydtase_PyrdxlP-BS
IPR036052 Trypto_synt_PLP_dependent
PANTHERiPTHR43419:SF2 PTHR43419:SF2, 1 hit
PfamiView protein in Pfam
PF00291 PALP, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR02035 D_Ser_am_lyase, 1 hit
PROSITEiView protein in PROSITE
PS00165 DEHYDRATASE_SER_THR, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XCK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENAKMNSLI AQYPLVKDLV ALKETTWFNP GTTSLAEGLP YVGLTEQDVQ
60 70 80 90 100
DAHARLSRFA PYLAKAFPET AATGGIIESE LVAIPAMQKR LEKEYQQPIS
110 120 130 140 150
GQLLLKKDSH LPISGSIKAR GGIYEVLAHA EKLALEAGLL TLEDDYSKLL
160 170 180 190 200
SPEFKQFFSQ YSIAVGSTGN LGLSIGIMSA RIGFKVTVHM SADARAWKKA
210 220 230 240 250
KLRSHGVTVV EYEQDYGVAV EEGRKAAQSD PNCFFIDDEN SRTLFLGYSV
260 270 280 290 300
AGQRLKAQFA EQGRIVDADN PLFVYLPCGV GGGPGGVAFG LKLAFGDHVH
310 320 330 340 350
CFFAEPTHSP CMLLGVHTGL HDQISVQDIG IDNLTAADGL AVGRASGFVG
360 370 380 390 400
RAMERLLDGF YTLSDQTMYD MLGWLAQEEG IRLEPSALAG MAGPQRVCAS
410 420 430 440
VSYQQMHGFS AEQLRNATHL VWATGGGMVP EEEMEQYLAK GR
Length:442
Mass (Da):47,901
Last modified:March 1, 2002 - v1
Checksum:i96CD7BA3E8C61BAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG57491.1
BA000007 Genomic DNA Translation: BAB36668.1
PIRiE91034
G85878
RefSeqiNP_311272.1, NC_002695.1
WP_000426437.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG57491; AAG57491; Z3628
BAB36668; BAB36668; BAB36668
GeneIDi915655
KEGGiece:Z3628
ecs:ECs3245
PATRICifig|386585.9.peg.3389

Similar proteinsi

Entry informationi

Entry nameiSDHD_ECO57
AccessioniPrimary (citable) accession number: Q8XCK5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: March 1, 2002
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health