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Protein

L(+)-tartrate dehydratase subunit beta

Gene

ttdB

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(R,R)-tartrate = oxaloacetate + H2O.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei37Sequence analysis1

GO - Molecular functioni

Keywordsi

Molecular functionLyase

Names & Taxonomyi

Protein namesi
Recommended name:
L(+)-tartrate dehydratase subunit beta (EC:4.2.1.32)
Short name:
L-TTD beta
Gene namesi
Name:ttdB
Ordered Locus Names:Z4415, ECs3945
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001956651 – 201L(+)-tartrate dehydratase subunit betaAdd BLAST201

Expressioni

Inductioni

Induced by tartrate, via TtdR.By similarity

Interactioni

Subunit structurei

Heterotetramer of two alpha and two beta subunits.By similarity

Protein-protein interaction databases

STRINGi155864.Z4415

Structurei

3D structure databases

ProteinModelPortaliQ8XBK5
SMRiQ8XBK5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-I fumarase family.Curated

Phylogenomic databases

eggNOGiENOG4107GFK Bacteria
COG1838 LUCA
HOGENOMiHOG000225718
KOiK03780
OMAiIYHAGPI

Family and domain databases

Gene3Di3.20.130.10, 1 hit
InterProiView protein in InterPro
IPR004647 Fe-S_hydro-lyase_TtdB-typ_cat
IPR036660 Fe-S_hydroAse_TtdB_cat_sf
PfamiView protein in Pfam
PF05683 Fumerase_C, 1 hit
SUPFAMiSSF117457 SSF117457, 1 hit
TIGRFAMsiTIGR00723 ttdB_fumA_fumB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XBK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKILTTPIK AEDLQDIHVG DVIYLTGTLV TCRDVCHRRL IELKRPLPYD
60 70 80 90 100
LNGKAIFHAG PIVRKNGDKW EMVSVGPTTS MRMESFEREF IEQTGVKLVV
110 120 130 140 150
GKGGMGPLTE EGCQKFKALH VIFPAGCAVL AATQVEEIEE VHWTELGMPE
160 170 180 190 200
SLWVCRVKEF GPLIVSIDTH GNNLIAENKK LFAERRDPIV EEICEHVHYI

K
Length:201
Mass (Da):22,660
Last modified:March 1, 2002 - v1
Checksum:i451BA605C388F157
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58196.1
BA000007 Genomic DNA Translation: BAB37368.1
PIRiA91122
H85966
RefSeqiNP_311972.1, NC_002695.1
WP_000722948.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58196; AAG58196; Z4415
BAB37368; BAB37368; BAB37368
GeneIDi916229
KEGGiece:Z4415
ecs:ECs3945
PATRICifig|386585.9.peg.4115

Entry informationi

Entry nameiTTDB_ECO57
AccessioniPrimary (citable) accession number: Q8XBK5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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