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Q8XBK5

- TTDB_ECO57

UniProt

Q8XBK5 - TTDB_ECO57

Protein

L(+)-tartrate dehydratase subunit beta

Gene

ttdB

Organism
Escherichia coli O157:H7
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (R,R)-tartrate = oxaloacetate + H2O.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei37 – 371Sequence Analysis

    GO - Molecular functioni

    1. L(+)-tartrate dehydratase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Lyase

    Enzyme and pathway databases

    BioCyciECOL386585:GJFA-3904-MONOMER.
    ECOO157:TTDB-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    L(+)-tartrate dehydratase subunit beta (EC:4.2.1.32)
    Short name:
    L-TTD beta
    Gene namesi
    Name:ttdB
    Ordered Locus Names:Z4415, ECs3945
    OrganismiEscherichia coli O157:H7
    Taxonomic identifieri83334 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000558: Chromosome, UP000002519: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 201201L(+)-tartrate dehydratase subunit betaPRO_0000195665Add
    BLAST

    Expressioni

    Inductioni

    Induced by tartrate, via TtdR.By similarity

    Interactioni

    Subunit structurei

    Heterotetramer of two alpha and two beta subunits.By similarity

    Protein-protein interaction databases

    STRINGi155864.Z4415.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8XBK5.
    SMRiQ8XBK5. Positions 1-177.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-I fumarase family.Curated

    Phylogenomic databases

    eggNOGiCOG1838.
    HOGENOMiHOG000225718.
    KOiK03780.
    OMAiEWQDLGM.
    OrthoDBiEOG6TXR10.

    Family and domain databases

    Gene3Di3.20.130.10. 1 hit.
    InterProiIPR004647. Fe-S_hydro-lyase_TtdB-typ_cat.
    [Graphical view]
    PfamiPF05683. Fumerase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF117457. SSF117457. 1 hit.
    TIGRFAMsiTIGR00723. ttdB_fumA_fumB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8XBK5-1 [UniParc]FASTAAdd to Basket

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    MKKILTTPIK AEDLQDIHVG DVIYLTGTLV TCRDVCHRRL IELKRPLPYD    50
    LNGKAIFHAG PIVRKNGDKW EMVSVGPTTS MRMESFEREF IEQTGVKLVV 100
    GKGGMGPLTE EGCQKFKALH VIFPAGCAVL AATQVEEIEE VHWTELGMPE 150
    SLWVCRVKEF GPLIVSIDTH GNNLIAENKK LFAERRDPIV EEICEHVHYI 200
    K 201
    Length:201
    Mass (Da):22,660
    Last modified:March 1, 2002 - v1
    Checksum:i451BA605C388F157
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005174 Genomic DNA. Translation: AAG58196.1.
    BA000007 Genomic DNA. Translation: BAB37368.1.
    PIRiA91122.
    H85966.
    RefSeqiNP_289637.1. NC_002655.2.
    NP_311972.1. NC_002695.1.

    Genome annotation databases

    EnsemblBacteriaiAAG58196; AAG58196; Z4415.
    BAB37368; BAB37368; BAB37368.
    GeneIDi916229.
    958372.
    KEGGiece:Z4415.
    ecs:ECs3945.
    PATRICi18357385. VBIEscCol44059_3870.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE005174 Genomic DNA. Translation: AAG58196.1 .
    BA000007 Genomic DNA. Translation: BAB37368.1 .
    PIRi A91122.
    H85966.
    RefSeqi NP_289637.1. NC_002655.2.
    NP_311972.1. NC_002695.1.

    3D structure databases

    ProteinModelPortali Q8XBK5.
    SMRi Q8XBK5. Positions 1-177.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 155864.Z4415.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG58196 ; AAG58196 ; Z4415 .
    BAB37368 ; BAB37368 ; BAB37368 .
    GeneIDi 916229.
    958372.
    KEGGi ece:Z4415.
    ecs:ECs3945.
    PATRICi 18357385. VBIEscCol44059_3870.

    Phylogenomic databases

    eggNOGi COG1838.
    HOGENOMi HOG000225718.
    KOi K03780.
    OMAi EWQDLGM.
    OrthoDBi EOG6TXR10.

    Enzyme and pathway databases

    BioCyci ECOL386585:GJFA-3904-MONOMER.
    ECOO157:TTDB-MONOMER.

    Family and domain databases

    Gene3Di 3.20.130.10. 1 hit.
    InterProi IPR004647. Fe-S_hydro-lyase_TtdB-typ_cat.
    [Graphical view ]
    Pfami PF05683. Fumerase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117457. SSF117457. 1 hit.
    TIGRFAMsi TIGR00723. ttdB_fumA_fumB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
    2. "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
      Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.
      , Kuhara S., Shiba T., Hattori M., Shinagawa H.
      DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

    Entry informationi

    Entry nameiTTDB_ECO57
    AccessioniPrimary (citable) accession number: Q8XBK5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 28, 2003
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3