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Q8XBK5 (TTDB_ECO57) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
L(+)-tartrate dehydratase subunit beta

Short name=L-TTD beta
EC=4.2.1.32
Gene names
Name:ttdB
Ordered Locus Names:Z4415, ECs3945
OrganismEscherichia coli O157:H7 [Complete proteome] [HAMAP]
Taxonomic identifier83334 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length201 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(R,R)-tartrate = oxaloacetate + H2O.

Subunit structure

Heterotetramer of two alpha and two beta subunits By similarity.

Induction

Induced by tartrate, via TtdR By similarity.

Sequence similarities

Belongs to the class-I fumarase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmetabolic process

Inferred from electronic annotation. Source: GOC

   Molecular_functionL(+)-tartrate dehydratase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 201201L(+)-tartrate dehydratase subunit beta
PRO_0000195665

Sites

Active site371 Potential

Sequences

Sequence LengthMass (Da)Tools
Q8XBK5 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 451BA605C388F157

FASTA20122,660
        10         20         30         40         50         60 
MKKILTTPIK AEDLQDIHVG DVIYLTGTLV TCRDVCHRRL IELKRPLPYD LNGKAIFHAG 

        70         80         90        100        110        120 
PIVRKNGDKW EMVSVGPTTS MRMESFEREF IEQTGVKLVV GKGGMGPLTE EGCQKFKALH 

       130        140        150        160        170        180 
VIFPAGCAVL AATQVEEIEE VHWTELGMPE SLWVCRVKEF GPLIVSIDTH GNNLIAENKK 

       190        200 
LFAERRDPIV EEICEHVHYI K 

« Hide

References

[1]"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7."
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. expand/collapse author list , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.
Nature 409:529-533(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.
[2]"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. expand/collapse author list , Kuhara S., Shiba T., Hattori M., Shinagawa H.
DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE005174 Genomic DNA. Translation: AAG58196.1.
BA000007 Genomic DNA. Translation: BAB37368.1.
PIRA91122.
H85966.
RefSeqNP_289637.1. NC_002655.2.
NP_311972.1. NC_002695.1.

3D structure databases

ProteinModelPortalQ8XBK5.
SMRQ8XBK5. Positions 1-177.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING155864.Z4415.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAG58196; AAG58196; Z4415.
BAB37368; BAB37368; BAB37368.
GeneID916229.
958372.
KEGGece:Z4415.
ecs:ECs3945.
PATRIC18357385. VBIEscCol44059_3870.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1838.
HOGENOMHOG000225718.
KOK03780.
OMAVENFGPL.
OrthoDBEOG6TXR10.
ProtClustDBPRK08228.

Enzyme and pathway databases

BioCycECOL386585:GJFA-3904-MONOMER.
ECOO157:TTDB-MONOMER.

Family and domain databases

Gene3D3.20.130.10. 1 hit.
InterProIPR004647. Fe-S_hydro-lyase_TtdB-typ_cat.
[Graphical view]
PfamPF05683. Fumerase_C. 1 hit.
[Graphical view]
SUPFAMSSF117457. SSF117457. 1 hit.
TIGRFAMsTIGR00723. ttdB_fumA_fumB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTTDB_ECO57
AccessionPrimary (citable) accession number: Q8XBK5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 28, 2003
Last sequence update: March 1, 2002
Last modified: February 19, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families