Q8XB99 (MPGP_ECO57) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative mannosyl-3-phosphoglycerate phosphatase
Short name=MPGP
EC=3.1.3.70

Gene names

Name:	yedP
Ordered Locus Names:	Z3045, ECs2693

Organism

Escherichia coli O157:H7 [Complete proteome] [HAMAP]

Taxonomic identifier

83334 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2(alpha-D-mannosyl)-D-glycerate + phosphate. HAMAP-Rule MF_00617
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the HAD-like hydrolase superfamily. MPGP family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dephosphorylation Inferred from electronic annotation. Source: GOC mannosylglycerate biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	mannosyl-3-phosphoglycerate phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 271	271	Putative mannosyl-3-phosphoglycerate phosphatase HAMAP-Rule MF_00617		PRO_0000184976

Sequences

	Sequence		Length	Mass (Da)
	Q8XB99 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 3D5D719F742ADF84	FASTA	271	30,470
	10 20 30 40 50 60 MFSIQQPLLV FSDLDGTLLD SHSYDWQPAA PWLSRLREAN VPVILCSSKT SAEMLYLQKM 70 80 90 100 110 120 LGLQGLPLIA ENGAVIQLAE QWQEIDGFPR IISGISHGEI SQVLNTLREK EHFKFTTFDD 130 140 150 160 170 180 VDDATIAEWT GLSRSQAALT QLHEASVTLI WRDSDERMAQ FTARLNELGL QFMQGARFWH 190 200 210 220 230 240 VLDASAGKDQ AANWIIATYQ QLSGKRPTTL GLGDGPNDAP LLEVMDYAVI VKGLNREGVH 250 260 270 LHDEDPARVW RTQREGPEGW REGLDHFFSA R

References

[1]

"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R. Nature 409:529-533(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.

[2]

"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12." Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T. , Kuhara S., Shiba T., Hattori M., Shinagawa H. DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / Sakai / RIMD 0509952 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005174 Genomic DNA. Translation: AAG56969.1. BA000007 Genomic DNA. Translation: BAB36116.1.
PIR	E85813. E90965.
RefSeq	NP_288415.1. NC_002655.2. NP_310720.1. NC_002695.1.
3D structure databases
ProteinModelPortal	Q8XB99.
SMR	Q8XB99. Positions 1-234.
ModBase	Search...
Protein-protein interaction databases
STRING	155864.Z3045.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAG56969; AAG56969; Z3045. BAB36116; BAB36116; BAB36116.
GeneID	913699. 961955.
KEGG	ece:Z3045. ecs:ECs2693.
PATRIC	18354772. VBIEscCol44059_2594.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3769.
HOGENOM	HOG000224319.
KO	K07026.
OMA	IPCTSKT.
ProtClustDB	PRK03669.
Enzyme and pathway databases
BioCyc	ECOL386585:GJFA-2657-MONOMER.
Family and domain databases
Gene3D	3.40.50.1000. 2 hits.
HAMAP	MF_00617. MPGP_rel.
InterPro	IPR023214. HAD-like_dom. IPR006379. HAD-SF_hydro_IIB. IPR006381. HAD-SF_hydro_IIB_YedP. IPR012815. MPG_Pase. [Graphical view]
Pfam	PF08282. Hydrolase_3. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR01486. HAD-SF-IIB-MPGP. 1 hit. TIGR02463. MPGP_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MPGP_ECO57

Accession

Primary (citable) accession number: Q8XB99

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program