Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UPF0597 protein YhaM

Gene

yhaM

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Thought to be a D-serine dehydratase, however it does not complement a dsdA (D-serine dehydratase) mutant in strain CFT073, suggesting it may not have that function (PubMed:26727373).1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0597 protein YhaMUniRule annotation
Gene namesi
Name:yhaMUniRule annotation
Ordered Locus Names:Z4462, ECs3990
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

No effect on protein secretion by the type III secretion system (TTSS) encoded in the locus of effacement (LEE).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003398211 – 436UPF0597 protein YhaMAdd BLAST436

Expressioni

Inductioni

40-fold induced under conditions that maximally induce expression of the large pathogenicity island (PAI) also called the locus of effacement (LEE); part of the dlsT-yhaM operon. Slightly induced by D-serine.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi155864.Z4462

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0597 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CEM Bacteria
COG3681 LUCA
HOGENOMiHOG000237280
OMAiGAMIPVM

Family and domain databases

HAMAPiMF_01845 UPF0597, 1 hit
InterProiView protein in InterPro
IPR005130 Ser_deHydtase-like_asu
IPR021144 UPF0597
PANTHERiPTHR30501 PTHR30501, 1 hit
PfamiView protein in Pfam
PF03313 SDH_alpha, 1 hit
PIRSFiPIRSF006054 UCP006054, 1 hit

Sequencei

Sequence statusi: Complete.

Q8XAF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDSTLNPLW QRYILAVQEE VKPALGCTEP ISLALAAAVA AAELEGPVER
60 70 80 90 100
VEAWVSPNLM KNGLGVTVPG TGMVGLPIAA ALGALGGNAN AGLEVLKDAT
110 120 130 140 150
AQAIADAKAL LAAGKVSVKI QEPCNEILFS RAKVWNGEKW ACVTIVGGHT
160 170 180 190 200
NIVHIETHDG VVFTQQACVA EGEQESPLSV LSRTTLAEIL KFVNEVPFAA
210 220 230 240 250
IRFILDSAKL NCALSQEGLS GKWGLHIGAT LEKQCERGLL AKDLSSSIVI
260 270 280 290 300
RTSAASDARM GGATLPAMSN SGSGNQGITA TMPVVVVAEH FGADDERLAR
310 320 330 340 350
ALMLSHLSAI YIHNQLPRLS ALCAATTAAM GAAAGMAWLV DGRYETISMA
360 370 380 390 400
ISSMIGDVSG MICDGASNSC AMKVSTSASA AWKAVLMALD DTAVTGNEGI
410 420 430
VAHDVEQSIA NLCALASHSM QQTDRQIIEI MASKAR
Length:436
Mass (Da):45,346
Last modified:March 1, 2002 - v1
Checksum:iC7A5E9921C4CE45C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG58241.1
BA000007 Genomic DNA Translation: BAB37413.1
PIRiE85972
F91127
RefSeqiNP_312017.1, NC_002695.1
WP_000460512.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG58241; AAG58241; Z4462
BAB37413; BAB37413; BAB37413
GeneIDi916164
KEGGiece:Z4462
ecs:ECs3990
PATRICifig|386585.9.peg.4164

Similar proteinsi

Entry informationi

Entry nameiYHAM_ECO57
AccessioniPrimary (citable) accession number: Q8XAF6
Secondary accession number(s): Q7AAM1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health