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Protein

UPF0597 protein YhaM

Gene

yhaM

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Thought to be a D-serine dehydratase, however it does not complement a dsdA (D-serine dehydratase) mutant in strain CFT073, suggesting it may not have that function (PubMed:26727373).1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0597 protein YhaM
Gene namesi
Name:yhaM
Ordered Locus Names:Z4462, ECs3990
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

No effect on protein secretion by the type III secretion system (TTSS) encoded in the locus of effacement (LEE).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003398211 – 436UPF0597 protein YhaMAdd BLAST436

Expressioni

Inductioni

40-fold induced under conditions that maximally induce expression of the large pathogenicity island (PAI) also called the locus of effacement (LEE); part of the dlsT-yhaM operon. Slightly induced by D-serine.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi155864.Z4462.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0597 family.

Phylogenomic databases

eggNOGiENOG4105CEM. Bacteria.
COG3681. LUCA.
HOGENOMiHOG000237280.

Family and domain databases

HAMAPiMF_01845. UPF0597. 1 hit.
InterProiView protein in InterPro
IPR005130. Ser_deHydtase-like_asu.
IPR021144. UPF0597.
PfamiView protein in Pfam
PF03313. SDH_alpha. 1 hit.
PIRSFiPIRSF006054. UCP006054. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8XAF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDSTLNPLW QRYILAVQEE VKPALGCTEP ISLALAAAVA AAELEGPVER
60 70 80 90 100
VEAWVSPNLM KNGLGVTVPG TGMVGLPIAA ALGALGGNAN AGLEVLKDAT
110 120 130 140 150
AQAIADAKAL LAAGKVSVKI QEPCNEILFS RAKVWNGEKW ACVTIVGGHT
160 170 180 190 200
NIVHIETHDG VVFTQQACVA EGEQESPLSV LSRTTLAEIL KFVNEVPFAA
210 220 230 240 250
IRFILDSAKL NCALSQEGLS GKWGLHIGAT LEKQCERGLL AKDLSSSIVI
260 270 280 290 300
RTSAASDARM GGATLPAMSN SGSGNQGITA TMPVVVVAEH FGADDERLAR
310 320 330 340 350
ALMLSHLSAI YIHNQLPRLS ALCAATTAAM GAAAGMAWLV DGRYETISMA
360 370 380 390 400
ISSMIGDVSG MICDGASNSC AMKVSTSASA AWKAVLMALD DTAVTGNEGI
410 420 430
VAHDVEQSIA NLCALASHSM QQTDRQIIEI MASKAR
Length:436
Mass (Da):45,346
Last modified:March 1, 2002 - v1
Checksum:iC7A5E9921C4CE45C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG58241.1.
BA000007 Genomic DNA. Translation: BAB37413.1.
PIRiE85972.
F91127.
RefSeqiNP_312017.1. NC_002695.1.
WP_000460512.1. NZ_NOKN01000002.1.

Genome annotation databases

EnsemblBacteriaiAAG58241; AAG58241; Z4462.
BAB37413; BAB37413; BAB37413.
GeneIDi916164.
KEGGiece:Z4462.
ecs:ECs3990.
PATRICifig|386585.9.peg.4164.

Similar proteinsi

Entry informationi

Entry nameiYHAM_ECO57
AccessioniPrimary (citable) accession number: Q8XAF6
Secondary accession number(s): Q7AAM1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2002
Last modified: November 22, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries