Q8X944 (Q8X944_ECO57) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aldose 1-epimerase PIRNR PIRNR005096
EC=5.1.3.3 PIRNR PIRNR005096

Alternative name(s):
Galactose mutarotase PIRNR PIRNR005096

Gene names

Name:	galM EMBL AAG55085.1
Ordered Locus Names:	Z0926 EMBL AAG55085.1

Organism

Escherichia coli O157:H7 [Complete proteome] [HAMAP]

Taxonomic identifier

83334 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose By similarity. PIRNR PIRNR005096
Catalytic activity	Alpha-D-glucose = beta-D-glucose. PIRNR PIRNR005096
Pathway	Carbohydrate metabolism; hexose metabolism. PIRNR PIRNR005096
Sequence similarities	Belongs to the aldose epimerase family. PIRNR PIRNR005096

Ontologies

Keywords
Biological process	Carbohydrate metabolism PIRNR PIRNR005096
Molecular function	Isomerase PIRNR PIRNR005096
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	galactose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	aldose 1-epimerase activity Inferred from electronic annotation. Source: InterPro carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8X944 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: 133D0373211E7EFD	FASTA	346	38,170
	10 20 30 40 50 60 MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE 70 80 90 100 110 120 CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV NQLHGGPEGF DKRRWQIVNQ 130 140 150 160 170 180 NDRQVLFALS SDDGDQGFPG NLGATVXYRL TDDNRISITY RATVDKPCPV NMTNHVYFNL 190 200 210 220 230 240 DGKQSDVRNH KLQILADEYL PVDEGGIPHD GLKSVAGTSF DFRSAKIIAS EFLADDDQRK 250 260 270 280 290 300 VKGYDHAFLL QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNYLG GTPSRGTEPY 310 320 330 340 ADWQGLALES EFLPDSPNHP EWPQPDCFLH PGEEYSSLTE YQFIAE

References

[1]

"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7." Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W. , Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R. Nature 409:529-533(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: O157:H7 / EDL933 / ATCC 700927 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE005174 Genomic DNA. Translation: AAG55085.1.
PIR	A85578. H90726.
RefSeq	NP_286477.1. NC_002655.2.
3D structure databases
HSSP	HSSP built from PDB template 1MMU based on UniProtKB Q9ZB17.
ProteinModelPortal	Q8X944.
ModBase	Search...
Protein-protein interaction databases
STRING	155864.Z0926.
Proteomic databases
PRIDE	Q8X944.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAG55085; AAG55085; Z0926.
GeneID	957897.
KEGG	ece:Z0926.
PATRIC	18350606. VBIEscCol44059_0808.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000072798.
KO	K01785.
OMA	QLHSPDG.
ProtClustDB	PRK11055.
Enzyme and pathway databases
UniPathway	UPA00242.
Family and domain databases
Gene3D	2.70.98.10. 1 hit.
InterPro	IPR018052. Ald1_epimerase_CS. IPR013458. Ald_epimerase_bac. IPR015443. Aldose_1-epimerase. IPR008183. Aldose_1/G6P_1-epimerase. IPR011013. Gal_mutarotase_SF_dom. IPR014718. Glyco_hydro-type_carb-bd_sub. [Graphical view]
PANTHER	PTHR10091. PTHR10091. 1 hit.
Pfam	PF01263. Aldose_epim. 1 hit. [Graphical view]
PIRSF	PIRSF005096. GALM. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit.
TIGRFAMs	TIGR02636. galM_Leloir. 1 hit.
PROSITE	PS00545. ALDOSE_1_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8X944_ECO57

Accession

Primary (citable) accession number: Q8X944

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)