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Protein

Aldose 1-epimerase

Gene

galM

Organism
Escherichia coli O157:H7
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei175Proton donorUniRule annotation1
Binding sitei245SubstrateUniRule annotation1
Active sitei309Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation
Biological processCarbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:galMImported
Ordered Locus Names:Z0926Imported
OrganismiEscherichia coli O157:H7Imported
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ8X944.

Structurei

3D structure databases

ProteinModelPortaliQ8X944.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105ENN. Bacteria.
COG2017. LUCA.
HOGENOMiHOG000072798.
KOiK01785.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiView protein in InterPro
IPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. GH-type_carb-bd.
PfamiView protein in Pfam
PF01263. Aldose_epim. 1 hit.
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
TIGRFAMsiTIGR02636. galM_Leloir. 1 hit.
PROSITEiView protein in PROSITE
PS00545. ALDOSE_1_EPIMERASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8X944-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR
60 70 80 90 100
EALLGCASPE CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV
110 120 130 140 150
NQLHGGPEGF DKRRWQIVNQ NDRQVLFALS SDDGDQGFPG NLGATVXYRL
160 170 180 190 200
TDDNRISITY RATVDKPCPV NMTNHVYFNL DGKQSDVRNH KLQILADEYL
210 220 230 240 250
PVDEGGIPHD GLKSVAGTSF DFRSAKIIAS EFLADDDQRK VKGYDHAFLL
260 270 280 290 300
QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNYLG GTPSRGTEPY
310 320 330 340
ADWQGLALES EFLPDSPNHP EWPQPDCFLH PGEEYSSLTE YQFIAE
Length:346
Mass (Da):38,170
Last modified:July 5, 2004 - v2
Checksum:i133D0373211E7EFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA. Translation: AAG55085.1.
PIRiA85578.
H90726.

Genome annotation databases

EnsemblBacteriaiAAG55085; AAG55085; Z0926.
KEGGiece:Z0926.

Similar proteinsi

Entry informationi

Entry nameiQ8X944_ECO57
AccessioniPrimary (citable) accession number: Q8X944
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 86 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported