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Protein

Putative carboxymethylenebutenolidase

Gene

ysgA

Organism
Escherichia coli O157:H7
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei147By similarity1
Active sitei204By similarity1
Active sitei236By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Protein family/group databases

ESTHERiecoli-dlhh Dienelactone_hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative carboxymethylenebutenolidase (EC:3.1.1.45)
Alternative name(s):
Dienelactone hydrolase
Short name:
DLH
Gene namesi
Name:ysgA
Ordered Locus Names:Z5352, ECs4760
OrganismiEscherichia coli O157:H7
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome
  • UP000002519 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001615791 – 271Putative carboxymethylenebutenolidaseAdd BLAST271

Interactioni

Protein-protein interaction databases

STRINGi155864.Z5352

Structurei

3D structure databases

ProteinModelPortaliQ8X8L4
SMRiQ8X8L4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dienelactone hydrolase family.Curated

Phylogenomic databases

eggNOGiENOG4105CDZ Bacteria
COG0412 LUCA
HOGENOMiHOG000157123
KOiK01061
OMAiVHEHIAD

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR002925 Dienelactn_hydro
PfamiView protein in Pfam
PF01738 DLH, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

Q8X8L4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTQQSGFA PAASPLASTI VQTPDDAIVA GFTSIPSQGD NMPAYHARPK
60 70 80 90 100
QSDGPLPVVI VVQEIFGVHE HIRDICRRLA LEGYLAIAPE LYFREGDPND
110 120 130 140 150
FADIPTLLSG LVAKVPDSQV LADLDHVASW ASRNGGDVHR LMITGFCWGG
160 170 180 190 200
RITWLYAAHN PQLKAAVAWY GKLTGDKSLN SPKQPVDIAT DLNAPVLGLY
210 220 230 240 250
GGLDNSIPQE SVETMRQALR AANAKAEIIV YPDAGHAFNA DYRPSYHAAS
260 270
AEDGWQRMLE WFKQYGGKKS L
Length:271
Mass (Da):29,396
Last modified:February 21, 2002 - v1
Checksum:iA2FCEACBDC8F91E5
GO

Sequence cautioni

The sequence AAG59026 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB38183 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005174 Genomic DNA Translation: AAG59026.1 Different initiation.
BA000007 Genomic DNA Translation: BAB38183.1 Different initiation.
PIRiF86070
H91223
RefSeqiNP_312787.2, NC_002695.1
WP_001301462.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG59026; AAG59026; Z5352
BAB38183; BAB38183; BAB38183
GeneIDi915144
KEGGiece:Z5352
ecs:ECs4760
PATRICifig|386585.9.peg.4969

Similar proteinsi

Entry informationi

Entry nameiDLHH_ECO57
AccessioniPrimary (citable) accession number: Q8X8L4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: February 21, 2002
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health