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Protein

Pectinesterase

Gene

ECs0800

Organism
Escherichia coli O157:H7
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Pectin + n H2O = n methanol + pectate.UniRule annotation

Pathwayi: pectin degradation

This protein is involved in step 1 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase (ECs0800)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (kduI)
  5. no protein annotated in this organism
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl esteraseUniRule annotation, Hydrolase

Enzyme and pathway databases

UniPathwayiUPA00545; UER00823

Names & Taxonomyi

Protein namesi
Recommended name:
PectinesteraseUniRule annotation (EC:3.1.1.11UniRule annotation)
Gene namesi
Ordered Locus Names:ECs0800Imported
OrganismiEscherichia coli O157:H7Imported
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000558 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_501448279224 – 427PectinesteraseUniRule annotationAdd BLAST404

Interactioni

Protein-protein interaction databases

STRINGi155864.Z0943

Family & Domainsi

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG4105NBR Bacteria
COG4677 LUCA
KOiK01051
OMAiFNRMWEY

Family and domain databases

Gene3Di2.160.20.10, 1 hit
InterProiView protein in InterPro
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR033131 Pectinesterase_Asp_AS
IPR000070 Pectinesterase_cat
PfamiView protein in Pfam
PF01095 Pectinesterase, 1 hit
SUPFAMiSSF51126 SSF51126, 2 hits
PROSITEiView protein in PROSITE
PS00503 PECTINESTERASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8X891-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTFSVSRLA LALAFGVTLT ACSSTPPDQR PSDQTAPGTS SRPILSAKEA
60 70 80 90 100
QNFDAQHYFA SLTPGAAAWN PSPITLPAQP DFVVGPAGTQ GVTHTTIQAA
110 120 130 140 150
VDAAIIKRTN KRQYIAVMPG EYQGTVYVPA APGGITLYGT GEKPIDVKIG
160 170 180 190 200
LSLDGGMSPA DWRHDVNPRG KYMPGKPAWY MYDSCQSKRS DSIGVLCSAV
210 220 230 240 250
FWSQNNGLQL QNLTIENTLG DSVDAGNHPA VALRTDGDQV QINNVNILGR
260 270 280 290 300
QNTFFVTNSG VQNRLETNRQ PRTLVTNSYI EGDVDIVSGR GAVVFDNTEF
310 320 330 340 350
RVVNSRTQQE AYVFAPATLS NIYYGFLAVN SRFNASGDGV AQLGRSLDVD
360 370 380 390 400
ANTNGQVVIR DSAINEGFNT AKPWGDAVIS NRPFAGNTGS VDDSDEIQRN
410 420
LNDTNYNRMW EYNNRGVGSK VVAEAKK
Length:427
Mass (Da):45,981
Last modified:March 1, 2002 - v1
Checksum:i0B33AFA4BF594170
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000007 Genomic DNA Translation: BAB34223.1
RefSeqiNP_308827.1, NC_002695.1
WP_001091577.1, NZ_NOKN01000002.1

Genome annotation databases

EnsemblBacteriaiAAG55101; AAG55101; Z0943
BAB34223; BAB34223; BAB34223
GeneIDi917540
KEGGiece:Z0943
ecs:ECs0800
PATRICifig|386585.9.peg.921

Similar proteinsi

Entry informationi

Entry nameiQ8X891_ECO57
AccessioniPrimary (citable) accession number: Q8X891
Secondary accession number(s): Q7AGH4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: April 25, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health